Cargando…

The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review

Malnutrition and muscle wasting are associated with impaired physical functioning and quality of life in oncology patients. Patients diagnosed with upper gastrointestinal (GI) cancers are considered at high risk of malnutrition and impaired function. Due to continuous improvement in upper GI cancer...

Descripción completa

Detalles Bibliográficos
Autores principales: Sadeghi, Fatemeh, Mockler, David, Guinan, Emer M., Hussey, Juliette, Doyle, Suzanne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400981/
https://www.ncbi.nlm.nih.gov/pubmed/34445002
http://dx.doi.org/10.3390/nu13082842
_version_ 1783745442622734336
author Sadeghi, Fatemeh
Mockler, David
Guinan, Emer M.
Hussey, Juliette
Doyle, Suzanne L.
author_facet Sadeghi, Fatemeh
Mockler, David
Guinan, Emer M.
Hussey, Juliette
Doyle, Suzanne L.
author_sort Sadeghi, Fatemeh
collection PubMed
description Malnutrition and muscle wasting are associated with impaired physical functioning and quality of life in oncology patients. Patients diagnosed with upper gastrointestinal (GI) cancers are considered at high risk of malnutrition and impaired function. Due to continuous improvement in upper GI cancer survival rates, there has been an increased focus on multimodal interventions aimed at minimizing the adverse effects of cancer treatments and enhancing survivors’ quality of life. The present study aimed to evaluate the effectiveness of combined nutritional and exercise interventions in improving muscle wasting, physical functioning, and quality of life in patients with upper GI cancer. A comprehensive search was conducted in MEDLINE, EMBASE, Web of Science, Cochrane Library, and CINHAL. Of the 4780 identified articles, 148 were selected for full-text review, of which 5 studies met the inclusion criteria. Whilst reviewed studies showed promising effects of multimodal interventions on physical functioning, no significant differences in postoperative complications and hospital stay were observed. Limited available evidence showed conflicting results regarding the effectiveness of these interventions on preserving muscle mass and improving health-related quality of life. Further studies examining the impact of nutrition and exercise interventions on upper GI patient outcomes are required and would benefit from reporting a core outcome set.
format Online
Article
Text
id pubmed-8400981
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-84009812021-08-29 The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review Sadeghi, Fatemeh Mockler, David Guinan, Emer M. Hussey, Juliette Doyle, Suzanne L. Nutrients Systematic Review Malnutrition and muscle wasting are associated with impaired physical functioning and quality of life in oncology patients. Patients diagnosed with upper gastrointestinal (GI) cancers are considered at high risk of malnutrition and impaired function. Due to continuous improvement in upper GI cancer survival rates, there has been an increased focus on multimodal interventions aimed at minimizing the adverse effects of cancer treatments and enhancing survivors’ quality of life. The present study aimed to evaluate the effectiveness of combined nutritional and exercise interventions in improving muscle wasting, physical functioning, and quality of life in patients with upper GI cancer. A comprehensive search was conducted in MEDLINE, EMBASE, Web of Science, Cochrane Library, and CINHAL. Of the 4780 identified articles, 148 were selected for full-text review, of which 5 studies met the inclusion criteria. Whilst reviewed studies showed promising effects of multimodal interventions on physical functioning, no significant differences in postoperative complications and hospital stay were observed. Limited available evidence showed conflicting results regarding the effectiveness of these interventions on preserving muscle mass and improving health-related quality of life. Further studies examining the impact of nutrition and exercise interventions on upper GI patient outcomes are required and would benefit from reporting a core outcome set. MDPI 2021-08-18 /pmc/articles/PMC8400981/ /pubmed/34445002 http://dx.doi.org/10.3390/nu13082842 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Sadeghi, Fatemeh
Mockler, David
Guinan, Emer M.
Hussey, Juliette
Doyle, Suzanne L.
The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review
title The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review
title_full The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review
title_fullStr The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review
title_full_unstemmed The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review
title_short The Effectiveness of Nutrition Interventions Combined with Exercise in Upper Gastrointestinal Cancers: A Systematic Review
title_sort effectiveness of nutrition interventions combined with exercise in upper gastrointestinal cancers: a systematic review
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8400981/
https://www.ncbi.nlm.nih.gov/pubmed/34445002
http://dx.doi.org/10.3390/nu13082842
work_keys_str_mv AT sadeghifatemeh theeffectivenessofnutritioninterventionscombinedwithexerciseinuppergastrointestinalcancersasystematicreview
AT mocklerdavid theeffectivenessofnutritioninterventionscombinedwithexerciseinuppergastrointestinalcancersasystematicreview
AT guinanemerm theeffectivenessofnutritioninterventionscombinedwithexerciseinuppergastrointestinalcancersasystematicreview
AT husseyjuliette theeffectivenessofnutritioninterventionscombinedwithexerciseinuppergastrointestinalcancersasystematicreview
AT doylesuzannel theeffectivenessofnutritioninterventionscombinedwithexerciseinuppergastrointestinalcancersasystematicreview
AT sadeghifatemeh effectivenessofnutritioninterventionscombinedwithexerciseinuppergastrointestinalcancersasystematicreview
AT mocklerdavid effectivenessofnutritioninterventionscombinedwithexerciseinuppergastrointestinalcancersasystematicreview
AT guinanemerm effectivenessofnutritioninterventionscombinedwithexerciseinuppergastrointestinalcancersasystematicreview
AT husseyjuliette effectivenessofnutritioninterventionscombinedwithexerciseinuppergastrointestinalcancersasystematicreview
AT doylesuzannel effectivenessofnutritioninterventionscombinedwithexerciseinuppergastrointestinalcancersasystematicreview