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Studies of Interaction Mechanism between Pyrido [3,4-d] Pyrimidine Inhibitors and Mps1

Monopolar spindle 1 (Mps1), a dual-specific kinase, is related to the proper execution of chromosome biorientation and mitotic checkpoint signaling. The overexpression of Mps1 promotes the occurrence of cancer or the survival of aneuploid cancer cells, in other words, the reduction of Mps1 will seve...

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Detalles Bibliográficos
Autores principales:	Xing, Cheng, Zhou, Xiaoping, Chen, Chengjuan, Sun, Wei, Zheng, Qingchuan, Liang, Di
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401005/ https://www.ncbi.nlm.nih.gov/pubmed/34443663 http://dx.doi.org/10.3390/molecules26165075

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