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Investigation of Potential Reservoirs of Non-Tuberculous Mycobacteria in a European Sea Bass (Dicentrarchus labrax) Farm

Fish mycobacteriosis is a widespread global problem caused by species of non-tuberculous mycobacteria (NTM). Mycobacterium marinum is one of the species most often involved in disease episodes of aquarium and farmed fish. Since there is currently no available effective therapy or vaccine, a prompt s...

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Autores principales: Mugetti, Davide, Varello, Katia, Pastorino, Paolo, Tomasoni, Mattia, Menconi, Vasco, Bozzetta, Elena, Dondo, Alessandro, Prearo, Marino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401025/
https://www.ncbi.nlm.nih.gov/pubmed/34451479
http://dx.doi.org/10.3390/pathogens10081014
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author Mugetti, Davide
Varello, Katia
Pastorino, Paolo
Tomasoni, Mattia
Menconi, Vasco
Bozzetta, Elena
Dondo, Alessandro
Prearo, Marino
author_facet Mugetti, Davide
Varello, Katia
Pastorino, Paolo
Tomasoni, Mattia
Menconi, Vasco
Bozzetta, Elena
Dondo, Alessandro
Prearo, Marino
author_sort Mugetti, Davide
collection PubMed
description Fish mycobacteriosis is a widespread global problem caused by species of non-tuberculous mycobacteria (NTM). Mycobacterium marinum is one of the species most often involved in disease episodes of aquarium and farmed fish. Since there is currently no available effective therapy or vaccine, a prompt search for routes of entry is key to limiting the damage induced by the disease. Here we report a case of mycobacteriosis follow up in a European sea bass (Dicentrarchus labrax) farm located in Northern Italy, in which environmental samples and newly added fish batches were analyzed. Samples from fish present on the farm, sediment, and periphyton all resulted positive for M. marinum, whereas the new fish batches and the water samples resulted negative. The environmental resistance of NTM (alcohol-acid resistance, biofilm formation) and the lack of prophylactic and therapeutic strategies make these diseases difficult to manage. Prompt identification of biotic and abiotic reservoirs, combined with good zootechnical hygiene practices, are the most effective measures to control fish mycobacteriosis in intensive farms.
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spelling pubmed-84010252021-08-29 Investigation of Potential Reservoirs of Non-Tuberculous Mycobacteria in a European Sea Bass (Dicentrarchus labrax) Farm Mugetti, Davide Varello, Katia Pastorino, Paolo Tomasoni, Mattia Menconi, Vasco Bozzetta, Elena Dondo, Alessandro Prearo, Marino Pathogens Article Fish mycobacteriosis is a widespread global problem caused by species of non-tuberculous mycobacteria (NTM). Mycobacterium marinum is one of the species most often involved in disease episodes of aquarium and farmed fish. Since there is currently no available effective therapy or vaccine, a prompt search for routes of entry is key to limiting the damage induced by the disease. Here we report a case of mycobacteriosis follow up in a European sea bass (Dicentrarchus labrax) farm located in Northern Italy, in which environmental samples and newly added fish batches were analyzed. Samples from fish present on the farm, sediment, and periphyton all resulted positive for M. marinum, whereas the new fish batches and the water samples resulted negative. The environmental resistance of NTM (alcohol-acid resistance, biofilm formation) and the lack of prophylactic and therapeutic strategies make these diseases difficult to manage. Prompt identification of biotic and abiotic reservoirs, combined with good zootechnical hygiene practices, are the most effective measures to control fish mycobacteriosis in intensive farms. MDPI 2021-08-11 /pmc/articles/PMC8401025/ /pubmed/34451479 http://dx.doi.org/10.3390/pathogens10081014 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mugetti, Davide
Varello, Katia
Pastorino, Paolo
Tomasoni, Mattia
Menconi, Vasco
Bozzetta, Elena
Dondo, Alessandro
Prearo, Marino
Investigation of Potential Reservoirs of Non-Tuberculous Mycobacteria in a European Sea Bass (Dicentrarchus labrax) Farm
title Investigation of Potential Reservoirs of Non-Tuberculous Mycobacteria in a European Sea Bass (Dicentrarchus labrax) Farm
title_full Investigation of Potential Reservoirs of Non-Tuberculous Mycobacteria in a European Sea Bass (Dicentrarchus labrax) Farm
title_fullStr Investigation of Potential Reservoirs of Non-Tuberculous Mycobacteria in a European Sea Bass (Dicentrarchus labrax) Farm
title_full_unstemmed Investigation of Potential Reservoirs of Non-Tuberculous Mycobacteria in a European Sea Bass (Dicentrarchus labrax) Farm
title_short Investigation of Potential Reservoirs of Non-Tuberculous Mycobacteria in a European Sea Bass (Dicentrarchus labrax) Farm
title_sort investigation of potential reservoirs of non-tuberculous mycobacteria in a european sea bass (dicentrarchus labrax) farm
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401025/
https://www.ncbi.nlm.nih.gov/pubmed/34451479
http://dx.doi.org/10.3390/pathogens10081014
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