Transcriptional epigenetic regulation of Fkbp1/Pax9 genes is associated with impaired sensitivity to platinum treatment in ovarian cancer

BACKGROUND: In an effort to contribute to overcoming the platinum resistance exhibited by most solid tumors, we performed an array of epigenetic approaches, integrating next-generation methodologies and public clinical data to identify new potential epi-biomarkers in ovarian cancer, which is conside...

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Detalles Bibliográficos
Autores principales: Soto, Javier Andrés, Rodríguez-Antolín, Carlos, Vera, Olga, Pernía, Olga, Esteban-Rodríguez, Isabel, Dolores Diestro, Maria, Benitez, Javier, Sánchez-Cabo, Fátima, Alvarez, Rafael, De Castro, Javier, Ibanez de Cáceres, Inmaculada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401184/
https://www.ncbi.nlm.nih.gov/pubmed/34454589
http://dx.doi.org/10.1186/s13148-021-01149-8

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