Intracellular S. aureus in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report

The pathophysiological role of intracellular bacteria in osteomyelitis is still a matter of debate. Here, we demonstrate for the first time the presence of Staphylococcus aureus internalized into osteoblasts in human tissue samples of a case with a chronic osteomyelitis using ultrastructural transmi...

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Autores principales: Walter, Nike, Mendelsohn, Daniel, Brochhausen, Christoph, Rupp, Markus, Alt, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401219/
https://www.ncbi.nlm.nih.gov/pubmed/34451528
http://dx.doi.org/10.3390/pathogens10081064
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author Walter, Nike
Mendelsohn, Daniel
Brochhausen, Christoph
Rupp, Markus
Alt, Volker
author_facet Walter, Nike
Mendelsohn, Daniel
Brochhausen, Christoph
Rupp, Markus
Alt, Volker
author_sort Walter, Nike
collection PubMed
description The pathophysiological role of intracellular bacteria in osteomyelitis is still a matter of debate. Here, we demonstrate for the first time the presence of Staphylococcus aureus internalized into osteoblasts in human tissue samples of a case with a chronic osteomyelitis using ultrastructural transmission electron microscope analysis.
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spelling pubmed-84012192021-08-29 Intracellular S. aureus in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report Walter, Nike Mendelsohn, Daniel Brochhausen, Christoph Rupp, Markus Alt, Volker Pathogens Case Report The pathophysiological role of intracellular bacteria in osteomyelitis is still a matter of debate. Here, we demonstrate for the first time the presence of Staphylococcus aureus internalized into osteoblasts in human tissue samples of a case with a chronic osteomyelitis using ultrastructural transmission electron microscope analysis. MDPI 2021-08-22 /pmc/articles/PMC8401219/ /pubmed/34451528 http://dx.doi.org/10.3390/pathogens10081064 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Walter, Nike
Mendelsohn, Daniel
Brochhausen, Christoph
Rupp, Markus
Alt, Volker
Intracellular S. aureus in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title Intracellular S. aureus in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title_full Intracellular S. aureus in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title_fullStr Intracellular S. aureus in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title_full_unstemmed Intracellular S. aureus in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title_short Intracellular S. aureus in Osteoblasts in a Clinical Sample from a Patient with Chronic Osteomyelitis—A Case Report
title_sort intracellular s. aureus in osteoblasts in a clinical sample from a patient with chronic osteomyelitis—a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401219/
https://www.ncbi.nlm.nih.gov/pubmed/34451528
http://dx.doi.org/10.3390/pathogens10081064
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