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Freeze-Dried Mesenchymal Stem Cell-Secretome Pharmaceuticalization: Optimization of Formulation and Manufacturing Process Robustness

Producing mesenchymal stem cell (MSC)-secretome for dose escalation studies and clinical practice requires scalable and good manufacturing practice (GMP)-compliant production procedures and formulation into a standardized medicinal product. Starting from a method that combines ultrafiltration and fr...

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Detalles Bibliográficos
Autores principales:	Mocchi, Michela, Bari, Elia, Marrubini, Giorgio, Bonda, Andrea Foglio, Perteghella, Sara, Tartara, Fulvio, Cofano, Fabio, Perna, Giuseppe di, Giovannelli, Lorella, Mandracchia, Delia, Sorlini, Marzio, Garbossa, Diego, Torre, Maria Luisa, Segale, Lorena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401234/ https://www.ncbi.nlm.nih.gov/pubmed/34452088 http://dx.doi.org/10.3390/pharmaceutics13081129

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