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Increasing uptake of colon cancer screening in a medically underserved population with the addition of blood-based testing

BACKGROUND: Adherence to colorectal cancer screening in the United States is suboptimal, particularly in medically underserved populations due to significant barriers to care. Unique accessible, low-cost, and non-invasive screening tests for this population could greatly benefit current rates. In th...

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Autores principales: Ioannou, Stephanie, Sutherland, Kyle, Sussman, Daniel A., Deshpande, Amar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401245/
https://www.ncbi.nlm.nih.gov/pubmed/34454457
http://dx.doi.org/10.1186/s12885-021-08678-8
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author Ioannou, Stephanie
Sutherland, Kyle
Sussman, Daniel A.
Deshpande, Amar R.
author_facet Ioannou, Stephanie
Sutherland, Kyle
Sussman, Daniel A.
Deshpande, Amar R.
author_sort Ioannou, Stephanie
collection PubMed
description BACKGROUND: Adherence to colorectal cancer screening in the United States is suboptimal, particularly in medically underserved populations due to significant barriers to care. Unique accessible, low-cost, and non-invasive screening tests for this population could greatly benefit current rates. In this article, we assess patient preference and the impact of offering a blood-based test on screening rates in a cost-free health fair setting from April 2017 to April 2019. METHODS: Participants who met colorectal cancer screening eligibility criteria set forth by the United States Preventive Services Task Force were recommended to attend the colon cancer screening station. Those participants who elected to attend were offered various, accepted screening methods, and if they declined, were offered alternative blood-based testing. Screening rates, test outcomes, and the rate of follow up completion of colonoscopy were measured and compared with historic screening outcomes. RESULTS: Of 1401 participants who were recommended to attend, 640 (45.7%) participants were evaluated at the colon cancer screening station, of whom 460 were eligible for testing. Amongst these, none selected colonoscopy, 30 (6.5%) selected fecal immunochemical testing, and 430 (93.5%) selected blood-based testing. Only 2 participants returned the fecal immunochemical tests. In the blood test cohort, 88 were positive and 20 received a follow up colonoscopy. CONCLUSIONS: Based on this assessment, blood-based testing is an effective method to increase screening rates in medically underserved populations, though efforts to further improve access to follow up colonoscopy are necessary. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12885-021-08678-8.
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spelling pubmed-84012452021-08-30 Increasing uptake of colon cancer screening in a medically underserved population with the addition of blood-based testing Ioannou, Stephanie Sutherland, Kyle Sussman, Daniel A. Deshpande, Amar R. BMC Cancer Research Article BACKGROUND: Adherence to colorectal cancer screening in the United States is suboptimal, particularly in medically underserved populations due to significant barriers to care. Unique accessible, low-cost, and non-invasive screening tests for this population could greatly benefit current rates. In this article, we assess patient preference and the impact of offering a blood-based test on screening rates in a cost-free health fair setting from April 2017 to April 2019. METHODS: Participants who met colorectal cancer screening eligibility criteria set forth by the United States Preventive Services Task Force were recommended to attend the colon cancer screening station. Those participants who elected to attend were offered various, accepted screening methods, and if they declined, were offered alternative blood-based testing. Screening rates, test outcomes, and the rate of follow up completion of colonoscopy were measured and compared with historic screening outcomes. RESULTS: Of 1401 participants who were recommended to attend, 640 (45.7%) participants were evaluated at the colon cancer screening station, of whom 460 were eligible for testing. Amongst these, none selected colonoscopy, 30 (6.5%) selected fecal immunochemical testing, and 430 (93.5%) selected blood-based testing. Only 2 participants returned the fecal immunochemical tests. In the blood test cohort, 88 were positive and 20 received a follow up colonoscopy. CONCLUSIONS: Based on this assessment, blood-based testing is an effective method to increase screening rates in medically underserved populations, though efforts to further improve access to follow up colonoscopy are necessary. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12885-021-08678-8. BioMed Central 2021-08-28 /pmc/articles/PMC8401245/ /pubmed/34454457 http://dx.doi.org/10.1186/s12885-021-08678-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Ioannou, Stephanie
Sutherland, Kyle
Sussman, Daniel A.
Deshpande, Amar R.
Increasing uptake of colon cancer screening in a medically underserved population with the addition of blood-based testing
title Increasing uptake of colon cancer screening in a medically underserved population with the addition of blood-based testing
title_full Increasing uptake of colon cancer screening in a medically underserved population with the addition of blood-based testing
title_fullStr Increasing uptake of colon cancer screening in a medically underserved population with the addition of blood-based testing
title_full_unstemmed Increasing uptake of colon cancer screening in a medically underserved population with the addition of blood-based testing
title_short Increasing uptake of colon cancer screening in a medically underserved population with the addition of blood-based testing
title_sort increasing uptake of colon cancer screening in a medically underserved population with the addition of blood-based testing
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401245/
https://www.ncbi.nlm.nih.gov/pubmed/34454457
http://dx.doi.org/10.1186/s12885-021-08678-8
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