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Sphingosine-1-Phosphate Induces ATP Release via Volume-Regulated Anion Channels in Breast Cell Lines

High interstitial level of ATP and its lysate adenosine in the cancer microenvironment are considered a halo mark of cancer. Adenosine acts as a strong immune suppressor. However, the source of ATP release is unclear. We clarified the release of ATP via volume-regulated anion channels (VRACs) in bre...

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Detalles Bibliográficos
Autores principales: Furuya, Kishio, Hirata, Hiroaki, Kobayashi, Takeshi, Sokabe, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401269/
https://www.ncbi.nlm.nih.gov/pubmed/34440595
http://dx.doi.org/10.3390/life11080851

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