The “Undetermined Significance” of (18)F-FDG PET/CT or PET/MRI in Patients with Monoclonal Gammopathy of Undetermined Significance (MGUS)

Monoclonal gammopathy of undetermined significance (MGUS) is a highly prevalent condition with the possible risk of progression to multiple myeloma (MM) or a lymphoproliferative neoplasm in a small percentage of patients. Fluorine-18 fluorodeoxyglucose ((18)F-FDG) positron emission tomography/comput...

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Detalles Bibliográficos
Autores principales: Treglia, Giorgio, Bertagna, Francesco, Albano, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401289/
https://www.ncbi.nlm.nih.gov/pubmed/34441062
http://dx.doi.org/10.3390/medicina57080856
Descripción
Sumario:Monoclonal gammopathy of undetermined significance (MGUS) is a highly prevalent condition with the possible risk of progression to multiple myeloma (MM) or a lymphoproliferative neoplasm in a small percentage of patients. Fluorine-18 fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) or positron emission tomography/magnetic resonance imaging (PET/MRI) are imaging methods increasingly used in patients with MM. The aim of this communication is to underline that, taking into account current evidence-based data, compared to MM the role of (18)F-FDG PET/CT or PET/MRI in MGUS is still undetermined and more studies should be performed before suggesting (18)F-FDG PET/CT or PET/MRI for evaluation of MM progression in patients with MGUS.

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