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Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21–ACE2 signaling

Apoptosis, inflammation, and fibrosis contribute to vascular remodeling and injury. Elabela (ELA) serves as a crucial regulator to maintain vascular function and has been implicated in the pathogenesis of hypertensive vascular remodeling. This study aims to explore regulatory roles and underlying me...

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Detalles Bibliográficos
Autores principales: Song, Juan-Juan, Yang, Mei, Liu, Ying, Song, Jia-Wei, Liu, Xiao-Yan, Miao, Ran, Zhang, Zhen-Zhou, Liu, Yu, Fan, Yi-Fan, Zhang, Qian, Dong, Ying, Yang, Xin-Chun, Zhong, Jiu-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401356/
https://www.ncbi.nlm.nih.gov/pubmed/34453661
http://dx.doi.org/10.1007/s10735-021-10011-3