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Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy
Fewer studies compared the improvement of plasma lipid levels after different types of surgery, in particular compared to one-anastomosis gastric bypass (OAGB). The aim of our study was to investigate how laparoscopic sleeve gastrectomy (LSG) and OAGB impact on weight loss and lipid profile 18 month...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401377/ https://www.ncbi.nlm.nih.gov/pubmed/34444930 http://dx.doi.org/10.3390/nu13082770 |
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author | Bettini, Silvia Segato, Gianni Prevedello, Luca Fabris, Roberto Prà, Chiara Dal Zabeo, Eva Compagnin, Chiara De Luca, Fabio Finco, Cristiano Foletto, Mirto Vettor, Roberto Busetto, Luca |
author_facet | Bettini, Silvia Segato, Gianni Prevedello, Luca Fabris, Roberto Prà, Chiara Dal Zabeo, Eva Compagnin, Chiara De Luca, Fabio Finco, Cristiano Foletto, Mirto Vettor, Roberto Busetto, Luca |
author_sort | Bettini, Silvia |
collection | PubMed |
description | Fewer studies compared the improvement of plasma lipid levels after different types of surgery, in particular compared to one-anastomosis gastric bypass (OAGB). The aim of our study was to investigate how laparoscopic sleeve gastrectomy (LSG) and OAGB impact on weight loss and lipid profile 18 months after surgery, in patients with severe obesity. Forty-six patients treated with OAGB were matched to eighty-eight patients submitted to LSG. Weight loss after OAGB (33.2%) was more evident than after LSG (29.6%) (p = 0.024). The difference in the prevalence of dyslipidemia showed a statistically significant reduction only after OAGB (61% versus 22%, p < 0.001). After adjustment for delta body mass index (BMI), age and sex, we demonstrated a statistically significant decrease of the differences between the changes before and after (delta Δ) the two surgery procedures: Δ total cholesterol values (p < 0.001), Δ low density lipoprotein-cholesterol values (p < 0.001) and Δ triglycerides values (p = 0.007). Patients with severe obesity undergoing to OAGB presented a better improvement of lipid plasma values than LSG patients. The reduction of lipid plasma levels was independent of the significant decrease of BMI after surgery, of age and of sex. |
format | Online Article Text |
id | pubmed-8401377 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84013772021-08-29 Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy Bettini, Silvia Segato, Gianni Prevedello, Luca Fabris, Roberto Prà, Chiara Dal Zabeo, Eva Compagnin, Chiara De Luca, Fabio Finco, Cristiano Foletto, Mirto Vettor, Roberto Busetto, Luca Nutrients Article Fewer studies compared the improvement of plasma lipid levels after different types of surgery, in particular compared to one-anastomosis gastric bypass (OAGB). The aim of our study was to investigate how laparoscopic sleeve gastrectomy (LSG) and OAGB impact on weight loss and lipid profile 18 months after surgery, in patients with severe obesity. Forty-six patients treated with OAGB were matched to eighty-eight patients submitted to LSG. Weight loss after OAGB (33.2%) was more evident than after LSG (29.6%) (p = 0.024). The difference in the prevalence of dyslipidemia showed a statistically significant reduction only after OAGB (61% versus 22%, p < 0.001). After adjustment for delta body mass index (BMI), age and sex, we demonstrated a statistically significant decrease of the differences between the changes before and after (delta Δ) the two surgery procedures: Δ total cholesterol values (p < 0.001), Δ low density lipoprotein-cholesterol values (p < 0.001) and Δ triglycerides values (p = 0.007). Patients with severe obesity undergoing to OAGB presented a better improvement of lipid plasma values than LSG patients. The reduction of lipid plasma levels was independent of the significant decrease of BMI after surgery, of age and of sex. MDPI 2021-08-12 /pmc/articles/PMC8401377/ /pubmed/34444930 http://dx.doi.org/10.3390/nu13082770 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bettini, Silvia Segato, Gianni Prevedello, Luca Fabris, Roberto Prà, Chiara Dal Zabeo, Eva Compagnin, Chiara De Luca, Fabio Finco, Cristiano Foletto, Mirto Vettor, Roberto Busetto, Luca Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy |
title | Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy |
title_full | Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy |
title_fullStr | Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy |
title_full_unstemmed | Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy |
title_short | Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy |
title_sort | improvement of lipid profile after one-anastomosis gastric bypass compared to sleeve gastrectomy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401377/ https://www.ncbi.nlm.nih.gov/pubmed/34444930 http://dx.doi.org/10.3390/nu13082770 |
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