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Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy

Fewer studies compared the improvement of plasma lipid levels after different types of surgery, in particular compared to one-anastomosis gastric bypass (OAGB). The aim of our study was to investigate how laparoscopic sleeve gastrectomy (LSG) and OAGB impact on weight loss and lipid profile 18 month...

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Autores principales: Bettini, Silvia, Segato, Gianni, Prevedello, Luca, Fabris, Roberto, Prà, Chiara Dal, Zabeo, Eva, Compagnin, Chiara, De Luca, Fabio, Finco, Cristiano, Foletto, Mirto, Vettor, Roberto, Busetto, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401377/
https://www.ncbi.nlm.nih.gov/pubmed/34444930
http://dx.doi.org/10.3390/nu13082770
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author Bettini, Silvia
Segato, Gianni
Prevedello, Luca
Fabris, Roberto
Prà, Chiara Dal
Zabeo, Eva
Compagnin, Chiara
De Luca, Fabio
Finco, Cristiano
Foletto, Mirto
Vettor, Roberto
Busetto, Luca
author_facet Bettini, Silvia
Segato, Gianni
Prevedello, Luca
Fabris, Roberto
Prà, Chiara Dal
Zabeo, Eva
Compagnin, Chiara
De Luca, Fabio
Finco, Cristiano
Foletto, Mirto
Vettor, Roberto
Busetto, Luca
author_sort Bettini, Silvia
collection PubMed
description Fewer studies compared the improvement of plasma lipid levels after different types of surgery, in particular compared to one-anastomosis gastric bypass (OAGB). The aim of our study was to investigate how laparoscopic sleeve gastrectomy (LSG) and OAGB impact on weight loss and lipid profile 18 months after surgery, in patients with severe obesity. Forty-six patients treated with OAGB were matched to eighty-eight patients submitted to LSG. Weight loss after OAGB (33.2%) was more evident than after LSG (29.6%) (p = 0.024). The difference in the prevalence of dyslipidemia showed a statistically significant reduction only after OAGB (61% versus 22%, p < 0.001). After adjustment for delta body mass index (BMI), age and sex, we demonstrated a statistically significant decrease of the differences between the changes before and after (delta Δ) the two surgery procedures: Δ total cholesterol values (p < 0.001), Δ low density lipoprotein-cholesterol values (p < 0.001) and Δ triglycerides values (p = 0.007). Patients with severe obesity undergoing to OAGB presented a better improvement of lipid plasma values than LSG patients. The reduction of lipid plasma levels was independent of the significant decrease of BMI after surgery, of age and of sex.
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spelling pubmed-84013772021-08-29 Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy Bettini, Silvia Segato, Gianni Prevedello, Luca Fabris, Roberto Prà, Chiara Dal Zabeo, Eva Compagnin, Chiara De Luca, Fabio Finco, Cristiano Foletto, Mirto Vettor, Roberto Busetto, Luca Nutrients Article Fewer studies compared the improvement of plasma lipid levels after different types of surgery, in particular compared to one-anastomosis gastric bypass (OAGB). The aim of our study was to investigate how laparoscopic sleeve gastrectomy (LSG) and OAGB impact on weight loss and lipid profile 18 months after surgery, in patients with severe obesity. Forty-six patients treated with OAGB were matched to eighty-eight patients submitted to LSG. Weight loss after OAGB (33.2%) was more evident than after LSG (29.6%) (p = 0.024). The difference in the prevalence of dyslipidemia showed a statistically significant reduction only after OAGB (61% versus 22%, p < 0.001). After adjustment for delta body mass index (BMI), age and sex, we demonstrated a statistically significant decrease of the differences between the changes before and after (delta Δ) the two surgery procedures: Δ total cholesterol values (p < 0.001), Δ low density lipoprotein-cholesterol values (p < 0.001) and Δ triglycerides values (p = 0.007). Patients with severe obesity undergoing to OAGB presented a better improvement of lipid plasma values than LSG patients. The reduction of lipid plasma levels was independent of the significant decrease of BMI after surgery, of age and of sex. MDPI 2021-08-12 /pmc/articles/PMC8401377/ /pubmed/34444930 http://dx.doi.org/10.3390/nu13082770 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bettini, Silvia
Segato, Gianni
Prevedello, Luca
Fabris, Roberto
Prà, Chiara Dal
Zabeo, Eva
Compagnin, Chiara
De Luca, Fabio
Finco, Cristiano
Foletto, Mirto
Vettor, Roberto
Busetto, Luca
Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy
title Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy
title_full Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy
title_fullStr Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy
title_full_unstemmed Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy
title_short Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy
title_sort improvement of lipid profile after one-anastomosis gastric bypass compared to sleeve gastrectomy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401377/
https://www.ncbi.nlm.nih.gov/pubmed/34444930
http://dx.doi.org/10.3390/nu13082770
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