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Characterization and Evaluation of 3D-Printed Connectors for Microfluidics

3D printing is regarded as a useful tool for the fabrication of microfluidic connectors to overcome the challenges of time consumption, clogging, poor alignment and bulky fixtures existing for current interconnections. 3D-printed connectors without any additional components can be directly printed t...

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Detalles Bibliográficos
Autores principales: Xu, Qianwen, Lo, Jeffery C. C., Lee, Shiwei Ricky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401451/
https://www.ncbi.nlm.nih.gov/pubmed/34442496
http://dx.doi.org/10.3390/mi12080874
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author Xu, Qianwen
Lo, Jeffery C. C.
Lee, Shiwei Ricky
author_facet Xu, Qianwen
Lo, Jeffery C. C.
Lee, Shiwei Ricky
author_sort Xu, Qianwen
collection PubMed
description 3D printing is regarded as a useful tool for the fabrication of microfluidic connectors to overcome the challenges of time consumption, clogging, poor alignment and bulky fixtures existing for current interconnections. 3D-printed connectors without any additional components can be directly printed to substrate with an orifice by UV-assisted coaxial printing. This paper further characterized and evaluated 3D-printed connectors fabricated by the proposed method. A process window with an operable combination of flow rates was identified. The outer flow rate could control the inner channel dimensions of 3D-printed connectors, which were expected to achieve less geometric mismatch of flow paths in microfluidic interfaces. The achieved smallest inner channel diameter was around 120 µm. Furthermore, the withstood pressure of 3D-printed connectors was evaluated to exceed 450 kPa, which could enable microfluidic chips to work at normal pressure.
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spelling pubmed-84014512021-08-29 Characterization and Evaluation of 3D-Printed Connectors for Microfluidics Xu, Qianwen Lo, Jeffery C. C. Lee, Shiwei Ricky Micromachines (Basel) Article 3D printing is regarded as a useful tool for the fabrication of microfluidic connectors to overcome the challenges of time consumption, clogging, poor alignment and bulky fixtures existing for current interconnections. 3D-printed connectors without any additional components can be directly printed to substrate with an orifice by UV-assisted coaxial printing. This paper further characterized and evaluated 3D-printed connectors fabricated by the proposed method. A process window with an operable combination of flow rates was identified. The outer flow rate could control the inner channel dimensions of 3D-printed connectors, which were expected to achieve less geometric mismatch of flow paths in microfluidic interfaces. The achieved smallest inner channel diameter was around 120 µm. Furthermore, the withstood pressure of 3D-printed connectors was evaluated to exceed 450 kPa, which could enable microfluidic chips to work at normal pressure. MDPI 2021-07-26 /pmc/articles/PMC8401451/ /pubmed/34442496 http://dx.doi.org/10.3390/mi12080874 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Xu, Qianwen
Lo, Jeffery C. C.
Lee, Shiwei Ricky
Characterization and Evaluation of 3D-Printed Connectors for Microfluidics
title Characterization and Evaluation of 3D-Printed Connectors for Microfluidics
title_full Characterization and Evaluation of 3D-Printed Connectors for Microfluidics
title_fullStr Characterization and Evaluation of 3D-Printed Connectors for Microfluidics
title_full_unstemmed Characterization and Evaluation of 3D-Printed Connectors for Microfluidics
title_short Characterization and Evaluation of 3D-Printed Connectors for Microfluidics
title_sort characterization and evaluation of 3d-printed connectors for microfluidics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401451/
https://www.ncbi.nlm.nih.gov/pubmed/34442496
http://dx.doi.org/10.3390/mi12080874
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