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Characterization and Evaluation of 3D-Printed Connectors for Microfluidics
3D printing is regarded as a useful tool for the fabrication of microfluidic connectors to overcome the challenges of time consumption, clogging, poor alignment and bulky fixtures existing for current interconnections. 3D-printed connectors without any additional components can be directly printed t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401451/ https://www.ncbi.nlm.nih.gov/pubmed/34442496 http://dx.doi.org/10.3390/mi12080874 |
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author | Xu, Qianwen Lo, Jeffery C. C. Lee, Shiwei Ricky |
author_facet | Xu, Qianwen Lo, Jeffery C. C. Lee, Shiwei Ricky |
author_sort | Xu, Qianwen |
collection | PubMed |
description | 3D printing is regarded as a useful tool for the fabrication of microfluidic connectors to overcome the challenges of time consumption, clogging, poor alignment and bulky fixtures existing for current interconnections. 3D-printed connectors without any additional components can be directly printed to substrate with an orifice by UV-assisted coaxial printing. This paper further characterized and evaluated 3D-printed connectors fabricated by the proposed method. A process window with an operable combination of flow rates was identified. The outer flow rate could control the inner channel dimensions of 3D-printed connectors, which were expected to achieve less geometric mismatch of flow paths in microfluidic interfaces. The achieved smallest inner channel diameter was around 120 µm. Furthermore, the withstood pressure of 3D-printed connectors was evaluated to exceed 450 kPa, which could enable microfluidic chips to work at normal pressure. |
format | Online Article Text |
id | pubmed-8401451 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84014512021-08-29 Characterization and Evaluation of 3D-Printed Connectors for Microfluidics Xu, Qianwen Lo, Jeffery C. C. Lee, Shiwei Ricky Micromachines (Basel) Article 3D printing is regarded as a useful tool for the fabrication of microfluidic connectors to overcome the challenges of time consumption, clogging, poor alignment and bulky fixtures existing for current interconnections. 3D-printed connectors without any additional components can be directly printed to substrate with an orifice by UV-assisted coaxial printing. This paper further characterized and evaluated 3D-printed connectors fabricated by the proposed method. A process window with an operable combination of flow rates was identified. The outer flow rate could control the inner channel dimensions of 3D-printed connectors, which were expected to achieve less geometric mismatch of flow paths in microfluidic interfaces. The achieved smallest inner channel diameter was around 120 µm. Furthermore, the withstood pressure of 3D-printed connectors was evaluated to exceed 450 kPa, which could enable microfluidic chips to work at normal pressure. MDPI 2021-07-26 /pmc/articles/PMC8401451/ /pubmed/34442496 http://dx.doi.org/10.3390/mi12080874 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Xu, Qianwen Lo, Jeffery C. C. Lee, Shiwei Ricky Characterization and Evaluation of 3D-Printed Connectors for Microfluidics |
title | Characterization and Evaluation of 3D-Printed Connectors for Microfluidics |
title_full | Characterization and Evaluation of 3D-Printed Connectors for Microfluidics |
title_fullStr | Characterization and Evaluation of 3D-Printed Connectors for Microfluidics |
title_full_unstemmed | Characterization and Evaluation of 3D-Printed Connectors for Microfluidics |
title_short | Characterization and Evaluation of 3D-Printed Connectors for Microfluidics |
title_sort | characterization and evaluation of 3d-printed connectors for microfluidics |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401451/ https://www.ncbi.nlm.nih.gov/pubmed/34442496 http://dx.doi.org/10.3390/mi12080874 |
work_keys_str_mv | AT xuqianwen characterizationandevaluationof3dprintedconnectorsformicrofluidics AT lojefferycc characterizationandevaluationof3dprintedconnectorsformicrofluidics AT leeshiweiricky characterizationandevaluationof3dprintedconnectorsformicrofluidics |