Breast Cancer Cell-Derived Adenosine Enhances Generation and Suppressor Function of Human Adaptive Regulatory T Cells

Introduction: Adaptive regulatory T cells (Tr1) are induced in the periphery by environmental stimuli. CD73 expression and adenosine (ADO) production by tumor cells may influence Tr1 generation and their immunosuppressive activity. Material and Methods: Tr1 were generated in co-cultures of CD4+CD25n...

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Detalles Bibliográficos
Autores principales: Mandapathil, Magis, Szczepanski, Miroslaw J., Jackson, Edwin K., Lang, Stephan, Whiteside, Theresa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401826/
https://www.ncbi.nlm.nih.gov/pubmed/34442398
http://dx.doi.org/10.3390/jpm11080754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401826/
https://www.ncbi.nlm.nih.gov/pubmed/34442398
http://dx.doi.org/10.3390/jpm11080754

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