RNA Phage VLP-Based Vaccine Platforms

Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic,...

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Detalles Bibliográficos
Autores principales: Peabody, David S., Peabody, Julianne, Bradfute, Steven B., Chackerian, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401894/
https://www.ncbi.nlm.nih.gov/pubmed/34451861
http://dx.doi.org/10.3390/ph14080764
Descripción
Sumario:Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic, and chemical display methods.

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