RNA Phage VLP-Based Vaccine Platforms

Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic,...

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Detalles Bibliográficos
Autores principales: Peabody, David S., Peabody, Julianne, Bradfute, Steven B., Chackerian, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401894/
https://www.ncbi.nlm.nih.gov/pubmed/34451861
http://dx.doi.org/10.3390/ph14080764
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author Peabody, David S.
Peabody, Julianne
Bradfute, Steven B.
Chackerian, Bryce
author_facet Peabody, David S.
Peabody, Julianne
Bradfute, Steven B.
Chackerian, Bryce
author_sort Peabody, David S.
collection PubMed
description Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic, and chemical display methods.
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spelling pubmed-84018942021-08-29 RNA Phage VLP-Based Vaccine Platforms Peabody, David S. Peabody, Julianne Bradfute, Steven B. Chackerian, Bryce Pharmaceuticals (Basel) Review Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format. Here we update the current state of development of RNA phage VLPs as platforms for presentation of diverse antigens by genetic, enzymatic, and chemical display methods. MDPI 2021-08-04 /pmc/articles/PMC8401894/ /pubmed/34451861 http://dx.doi.org/10.3390/ph14080764 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Peabody, David S.
Peabody, Julianne
Bradfute, Steven B.
Chackerian, Bryce
RNA Phage VLP-Based Vaccine Platforms
title RNA Phage VLP-Based Vaccine Platforms
title_full RNA Phage VLP-Based Vaccine Platforms
title_fullStr RNA Phage VLP-Based Vaccine Platforms
title_full_unstemmed RNA Phage VLP-Based Vaccine Platforms
title_short RNA Phage VLP-Based Vaccine Platforms
title_sort rna phage vlp-based vaccine platforms
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401894/
https://www.ncbi.nlm.nih.gov/pubmed/34451861
http://dx.doi.org/10.3390/ph14080764
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