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Antitumor Activity of Nanoparticles Loaded with PHT-427, a Novel AKT/PDK1 Inhibitor, for the Treatment of Head and Neck Squamous Cell Carcinoma

Currently, new treatments are required to supplement the current standard of care for head and neck squamous cell carcinoma (HNSCC). The phosphatidylinositol3-kinase (PI3K) signaling pathway is commonly altered and activated in HNSCC. PHT-427 is a dual PI3K-mammalian target of the AKT/PDK1 inhibitor...

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Detalles Bibliográficos
Autores principales:	Yanes-Díaz, Joaquín, Palao-Suay, Raquel, Aguilar, María Rosa, Riestra-Ayora, Juan Ignacio, Ferruelo-Alonso, Antonio, Rojo del Olmo, Luis, Vázquez-Lasa, Blanca, Sanz-Fernández, Ricardo, Sánchez-Rodríguez, Carolina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401941/ https://www.ncbi.nlm.nih.gov/pubmed/34452203 http://dx.doi.org/10.3390/pharmaceutics13081242

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