Development, Characterization and In Vivo Pharmacokinetic Assessment of Rectal Suppositories Containing Combination Antiretroviral Drugs for HIV Prevention

Receptive anal intercourse (RAI) contributes significantly to HIV acquisition underscoring the need to develop HIV prevention options for populations engaging in RAI practices. We explored the feasibility of formulating rectal suppositories with potent antiviral drugs for on-demand use. A fixed-dose...

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Detalles Bibliográficos
Autores principales: Jhunjhunwala, Kunal, Dobard, Charles W., Sharma, Sunita, Makarova, Natalia, Holder, Angela, Dinh, Chuong, Mitchell, James, Wang, Lin, Zhang, Junmei, Patel, Sravan Kumar, Heneine, Walid, Rohan, Lisa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8401959/
https://www.ncbi.nlm.nih.gov/pubmed/34452070
http://dx.doi.org/10.3390/pharmaceutics13081110

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