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Synthesis and Biological Evaluation of a Radiolabeled PET (Positron Emission Tomography) Probe for Visualization of In Vivo α-Fucosidase Expression

The acidic hydrolase α-fucosidase (AF) is a biomarker for maladies such as cancer and inflammation. The most advanced probes for α-fucosidase are unfortunately constrained to ex vivo or in vitro applications. The in vivo detection and quantification of AF using positron emission tomography would all...

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Detalles Bibliográficos
Autores principales: Cotton, Jonathan, Goehring, Chris Marc, Kuehn, Anna, Maurer, Andreas, Fuchs, Kerstin, Pichler, Bernd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402005/
https://www.ncbi.nlm.nih.gov/pubmed/34451843
http://dx.doi.org/10.3390/ph14080745