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Synthesis and Biological Evaluation of a Radiolabeled PET (Positron Emission Tomography) Probe for Visualization of In Vivo α-Fucosidase Expression
The acidic hydrolase α-fucosidase (AF) is a biomarker for maladies such as cancer and inflammation. The most advanced probes for α-fucosidase are unfortunately constrained to ex vivo or in vitro applications. The in vivo detection and quantification of AF using positron emission tomography would all...
Autores principales: | Cotton, Jonathan, Goehring, Chris Marc, Kuehn, Anna, Maurer, Andreas, Fuchs, Kerstin, Pichler, Bernd J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402005/ https://www.ncbi.nlm.nih.gov/pubmed/34451843 http://dx.doi.org/10.3390/ph14080745 |
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