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IRF2BP2 Mutation Is Associated with Increased STAT1 and STAT5 Activation in Two Family Members with Inflammatory Conditions and Lymphopenia

Interferon regulatory factor 2 binding protein 2 (IRF2BP2) is a transcriptional coregulator that has an important role in the regulation of the immune response. IRF2BP2 has been associated with the Janus kinase (JAK)—signal transducers and activators of transcription (STAT) pathway, but its exact ro...

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Detalles Bibliográficos
Autores principales:	Palmroth, Maaria, Viskari, Hanna, Seppänen, Mikko R. J., Keskitalo, Salla, Virtanen, Anniina, Varjosalo, Markku, Silvennoinen, Olli, Isomäki, Pia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402006/ https://www.ncbi.nlm.nih.gov/pubmed/34451894 http://dx.doi.org/10.3390/ph14080797

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