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Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights
Chemically and biologically safe storage of solutions for medical uses is a daily concern for industry since decades and it appeared even more dramatic during the last two years of pandemia. Biological safety is readily reached by sterilization using γ-irradiation process. However, such a type of ir...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402025/ https://www.ncbi.nlm.nih.gov/pubmed/34451206 http://dx.doi.org/10.3390/polym13162671 |
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author | Gaston, Fanny Dupuy, Nathalie Girard-Perier, Nina Marque, Sylvain R. A. Dorey, Samuel |
author_facet | Gaston, Fanny Dupuy, Nathalie Girard-Perier, Nina Marque, Sylvain R. A. Dorey, Samuel |
author_sort | Gaston, Fanny |
collection | PubMed |
description | Chemically and biologically safe storage of solutions for medical uses is a daily concern for industry since decades and it appeared even more dramatic during the last two years of pandemia. Biological safety is readily reached by sterilization using γ-irradiation process. However, such a type of irradiation induces the degradation and the release of chemicals able to spoil the biological solutions. Surprisingly, there are no investigations on multi-layer films combining multi-technique and multi-method approaches to unveil the events occurring during γ-irradiation. Furthermore, our investigations are focuses on properties/events occurring at product, macromolecular, and molecular levels. |
format | Online Article Text |
id | pubmed-8402025 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84020252021-08-29 Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights Gaston, Fanny Dupuy, Nathalie Girard-Perier, Nina Marque, Sylvain R. A. Dorey, Samuel Polymers (Basel) Review Chemically and biologically safe storage of solutions for medical uses is a daily concern for industry since decades and it appeared even more dramatic during the last two years of pandemia. Biological safety is readily reached by sterilization using γ-irradiation process. However, such a type of irradiation induces the degradation and the release of chemicals able to spoil the biological solutions. Surprisingly, there are no investigations on multi-layer films combining multi-technique and multi-method approaches to unveil the events occurring during γ-irradiation. Furthermore, our investigations are focuses on properties/events occurring at product, macromolecular, and molecular levels. MDPI 2021-08-10 /pmc/articles/PMC8402025/ /pubmed/34451206 http://dx.doi.org/10.3390/polym13162671 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Gaston, Fanny Dupuy, Nathalie Girard-Perier, Nina Marque, Sylvain R. A. Dorey, Samuel Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights |
title | Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights |
title_full | Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights |
title_fullStr | Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights |
title_full_unstemmed | Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights |
title_short | Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights |
title_sort | investigations at the product, macromolecular, and molecular level of the physical and chemical properties of a γ-irradiated multilayer eva/evoh/eva film: comprehensive analysis and mechanistic insights |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402025/ https://www.ncbi.nlm.nih.gov/pubmed/34451206 http://dx.doi.org/10.3390/polym13162671 |
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