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Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights

Chemically and biologically safe storage of solutions for medical uses is a daily concern for industry since decades and it appeared even more dramatic during the last two years of pandemia. Biological safety is readily reached by sterilization using γ-irradiation process. However, such a type of ir...

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Autores principales: Gaston, Fanny, Dupuy, Nathalie, Girard-Perier, Nina, Marque, Sylvain R. A., Dorey, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402025/
https://www.ncbi.nlm.nih.gov/pubmed/34451206
http://dx.doi.org/10.3390/polym13162671
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author Gaston, Fanny
Dupuy, Nathalie
Girard-Perier, Nina
Marque, Sylvain R. A.
Dorey, Samuel
author_facet Gaston, Fanny
Dupuy, Nathalie
Girard-Perier, Nina
Marque, Sylvain R. A.
Dorey, Samuel
author_sort Gaston, Fanny
collection PubMed
description Chemically and biologically safe storage of solutions for medical uses is a daily concern for industry since decades and it appeared even more dramatic during the last two years of pandemia. Biological safety is readily reached by sterilization using γ-irradiation process. However, such a type of irradiation induces the degradation and the release of chemicals able to spoil the biological solutions. Surprisingly, there are no investigations on multi-layer films combining multi-technique and multi-method approaches to unveil the events occurring during γ-irradiation. Furthermore, our investigations are focuses on properties/events occurring at product, macromolecular, and molecular levels.
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spelling pubmed-84020252021-08-29 Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights Gaston, Fanny Dupuy, Nathalie Girard-Perier, Nina Marque, Sylvain R. A. Dorey, Samuel Polymers (Basel) Review Chemically and biologically safe storage of solutions for medical uses is a daily concern for industry since decades and it appeared even more dramatic during the last two years of pandemia. Biological safety is readily reached by sterilization using γ-irradiation process. However, such a type of irradiation induces the degradation and the release of chemicals able to spoil the biological solutions. Surprisingly, there are no investigations on multi-layer films combining multi-technique and multi-method approaches to unveil the events occurring during γ-irradiation. Furthermore, our investigations are focuses on properties/events occurring at product, macromolecular, and molecular levels. MDPI 2021-08-10 /pmc/articles/PMC8402025/ /pubmed/34451206 http://dx.doi.org/10.3390/polym13162671 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gaston, Fanny
Dupuy, Nathalie
Girard-Perier, Nina
Marque, Sylvain R. A.
Dorey, Samuel
Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights
title Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights
title_full Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights
title_fullStr Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights
title_full_unstemmed Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights
title_short Investigations at the Product, Macromolecular, and Molecular Level of the Physical and Chemical Properties of a γ-Irradiated Multilayer EVA/EVOH/EVA Film: Comprehensive Analysis and Mechanistic Insights
title_sort investigations at the product, macromolecular, and molecular level of the physical and chemical properties of a γ-irradiated multilayer eva/evoh/eva film: comprehensive analysis and mechanistic insights
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402025/
https://www.ncbi.nlm.nih.gov/pubmed/34451206
http://dx.doi.org/10.3390/polym13162671
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