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Recent Progress Concerning the N-Arylation of Indoles
This review summarizes the current state-of-the-art procedures in terms of the preparation of N-arylindoles. After a short introduction, the transition-metal-free procedures available for the N-arylation of indoles are briefly discussed. Then, the nickel-catalyzed and palladium-catalyzed N-arylation...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402097/ https://www.ncbi.nlm.nih.gov/pubmed/34443667 http://dx.doi.org/10.3390/molecules26165079 |
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author | Oeser, Petr Koudelka, Jakub Petrenko, Artem Tobrman, Tomáš |
author_facet | Oeser, Petr Koudelka, Jakub Petrenko, Artem Tobrman, Tomáš |
author_sort | Oeser, Petr |
collection | PubMed |
description | This review summarizes the current state-of-the-art procedures in terms of the preparation of N-arylindoles. After a short introduction, the transition-metal-free procedures available for the N-arylation of indoles are briefly discussed. Then, the nickel-catalyzed and palladium-catalyzed N-arylation of indoles are both discussed. In the next section, copper-catalyzed procedures for the N-arylation of indoles are described. The final section focuses on recent findings in the field of biologically active N-arylindoles. |
format | Online Article Text |
id | pubmed-8402097 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84020972021-08-29 Recent Progress Concerning the N-Arylation of Indoles Oeser, Petr Koudelka, Jakub Petrenko, Artem Tobrman, Tomáš Molecules Review This review summarizes the current state-of-the-art procedures in terms of the preparation of N-arylindoles. After a short introduction, the transition-metal-free procedures available for the N-arylation of indoles are briefly discussed. Then, the nickel-catalyzed and palladium-catalyzed N-arylation of indoles are both discussed. In the next section, copper-catalyzed procedures for the N-arylation of indoles are described. The final section focuses on recent findings in the field of biologically active N-arylindoles. MDPI 2021-08-22 /pmc/articles/PMC8402097/ /pubmed/34443667 http://dx.doi.org/10.3390/molecules26165079 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Oeser, Petr Koudelka, Jakub Petrenko, Artem Tobrman, Tomáš Recent Progress Concerning the N-Arylation of Indoles |
title | Recent Progress Concerning the N-Arylation of Indoles |
title_full | Recent Progress Concerning the N-Arylation of Indoles |
title_fullStr | Recent Progress Concerning the N-Arylation of Indoles |
title_full_unstemmed | Recent Progress Concerning the N-Arylation of Indoles |
title_short | Recent Progress Concerning the N-Arylation of Indoles |
title_sort | recent progress concerning the n-arylation of indoles |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402097/ https://www.ncbi.nlm.nih.gov/pubmed/34443667 http://dx.doi.org/10.3390/molecules26165079 |
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