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Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets

Curcuma longa is very well-known medicinal plant not only in the Asian hemisphere but also known across the globe for its therapeutic and medicinal benefits. The active moiety of Curcuma longa is curcumin and has gained importance in various treatments of various disorders such as antibacterial, ant...

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Autores principales: Chopra, Hitesh, Dey, Protity Shuvra, Das, Debashrita, Bhattacharya, Tanima, Shah, Muddaser, Mubin, Sidra, Maishu, Samka Peregrine, Akter, Rokeya, Rahman, Md. Habibur, Karthika, Chenmala, Murad, Waheed, Qusty, Naeem, Qusti, Safaa, Alshammari, Eida M., Batiha, Gaber El-Saber, Altalbawy, Farag M. A., Albooq, Mona I. M., Alamri, Badrieah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402133/
https://www.ncbi.nlm.nih.gov/pubmed/34443593
http://dx.doi.org/10.3390/molecules26164998
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author Chopra, Hitesh
Dey, Protity Shuvra
Das, Debashrita
Bhattacharya, Tanima
Shah, Muddaser
Mubin, Sidra
Maishu, Samka Peregrine
Akter, Rokeya
Rahman, Md. Habibur
Karthika, Chenmala
Murad, Waheed
Qusty, Naeem
Qusti, Safaa
Alshammari, Eida M.
Batiha, Gaber El-Saber
Altalbawy, Farag M. A.
Albooq, Mona I. M.
Alamri, Badrieah M.
author_facet Chopra, Hitesh
Dey, Protity Shuvra
Das, Debashrita
Bhattacharya, Tanima
Shah, Muddaser
Mubin, Sidra
Maishu, Samka Peregrine
Akter, Rokeya
Rahman, Md. Habibur
Karthika, Chenmala
Murad, Waheed
Qusty, Naeem
Qusti, Safaa
Alshammari, Eida M.
Batiha, Gaber El-Saber
Altalbawy, Farag M. A.
Albooq, Mona I. M.
Alamri, Badrieah M.
author_sort Chopra, Hitesh
collection PubMed
description Curcuma longa is very well-known medicinal plant not only in the Asian hemisphere but also known across the globe for its therapeutic and medicinal benefits. The active moiety of Curcuma longa is curcumin and has gained importance in various treatments of various disorders such as antibacterial, antiprotozoal, cancer, obesity, diabetics and wound healing applications. Several techniques had been exploited as reported by researchers for increasing the therapeutic potential and its pharmacological activity. Here, the dictum is the new room for the development of physicochemical, as well as biological, studies for the efficacy in target specificity. Here, we discussed nanoformulation techniques, which lend support to upgrade the characters to the curcumin such as enhancing bioavailability, increasing solubility, modifying metabolisms, and target specificity, prolonged circulation, enhanced permeation. Our manuscript tried to seek the attention of the researcher by framing some solutions of some existing troubleshoots of this bioactive component for enhanced applications and making the formulations feasible at an industrial production scale. This manuscript focuses on recent inventions as well, which can further be implemented at the community level.
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spelling pubmed-84021332021-08-29 Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets Chopra, Hitesh Dey, Protity Shuvra Das, Debashrita Bhattacharya, Tanima Shah, Muddaser Mubin, Sidra Maishu, Samka Peregrine Akter, Rokeya Rahman, Md. Habibur Karthika, Chenmala Murad, Waheed Qusty, Naeem Qusti, Safaa Alshammari, Eida M. Batiha, Gaber El-Saber Altalbawy, Farag M. A. Albooq, Mona I. M. Alamri, Badrieah M. Molecules Review Curcuma longa is very well-known medicinal plant not only in the Asian hemisphere but also known across the globe for its therapeutic and medicinal benefits. The active moiety of Curcuma longa is curcumin and has gained importance in various treatments of various disorders such as antibacterial, antiprotozoal, cancer, obesity, diabetics and wound healing applications. Several techniques had been exploited as reported by researchers for increasing the therapeutic potential and its pharmacological activity. Here, the dictum is the new room for the development of physicochemical, as well as biological, studies for the efficacy in target specificity. Here, we discussed nanoformulation techniques, which lend support to upgrade the characters to the curcumin such as enhancing bioavailability, increasing solubility, modifying metabolisms, and target specificity, prolonged circulation, enhanced permeation. Our manuscript tried to seek the attention of the researcher by framing some solutions of some existing troubleshoots of this bioactive component for enhanced applications and making the formulations feasible at an industrial production scale. This manuscript focuses on recent inventions as well, which can further be implemented at the community level. MDPI 2021-08-18 /pmc/articles/PMC8402133/ /pubmed/34443593 http://dx.doi.org/10.3390/molecules26164998 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chopra, Hitesh
Dey, Protity Shuvra
Das, Debashrita
Bhattacharya, Tanima
Shah, Muddaser
Mubin, Sidra
Maishu, Samka Peregrine
Akter, Rokeya
Rahman, Md. Habibur
Karthika, Chenmala
Murad, Waheed
Qusty, Naeem
Qusti, Safaa
Alshammari, Eida M.
Batiha, Gaber El-Saber
Altalbawy, Farag M. A.
Albooq, Mona I. M.
Alamri, Badrieah M.
Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets
title Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets
title_full Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets
title_fullStr Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets
title_full_unstemmed Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets
title_short Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets
title_sort curcumin nanoparticles as promising therapeutic agents for drug targets
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402133/
https://www.ncbi.nlm.nih.gov/pubmed/34443593
http://dx.doi.org/10.3390/molecules26164998
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