Cargando…
Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets
Curcuma longa is very well-known medicinal plant not only in the Asian hemisphere but also known across the globe for its therapeutic and medicinal benefits. The active moiety of Curcuma longa is curcumin and has gained importance in various treatments of various disorders such as antibacterial, ant...
Autores principales: | , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402133/ https://www.ncbi.nlm.nih.gov/pubmed/34443593 http://dx.doi.org/10.3390/molecules26164998 |
_version_ | 1783745715476889600 |
---|---|
author | Chopra, Hitesh Dey, Protity Shuvra Das, Debashrita Bhattacharya, Tanima Shah, Muddaser Mubin, Sidra Maishu, Samka Peregrine Akter, Rokeya Rahman, Md. Habibur Karthika, Chenmala Murad, Waheed Qusty, Naeem Qusti, Safaa Alshammari, Eida M. Batiha, Gaber El-Saber Altalbawy, Farag M. A. Albooq, Mona I. M. Alamri, Badrieah M. |
author_facet | Chopra, Hitesh Dey, Protity Shuvra Das, Debashrita Bhattacharya, Tanima Shah, Muddaser Mubin, Sidra Maishu, Samka Peregrine Akter, Rokeya Rahman, Md. Habibur Karthika, Chenmala Murad, Waheed Qusty, Naeem Qusti, Safaa Alshammari, Eida M. Batiha, Gaber El-Saber Altalbawy, Farag M. A. Albooq, Mona I. M. Alamri, Badrieah M. |
author_sort | Chopra, Hitesh |
collection | PubMed |
description | Curcuma longa is very well-known medicinal plant not only in the Asian hemisphere but also known across the globe for its therapeutic and medicinal benefits. The active moiety of Curcuma longa is curcumin and has gained importance in various treatments of various disorders such as antibacterial, antiprotozoal, cancer, obesity, diabetics and wound healing applications. Several techniques had been exploited as reported by researchers for increasing the therapeutic potential and its pharmacological activity. Here, the dictum is the new room for the development of physicochemical, as well as biological, studies for the efficacy in target specificity. Here, we discussed nanoformulation techniques, which lend support to upgrade the characters to the curcumin such as enhancing bioavailability, increasing solubility, modifying metabolisms, and target specificity, prolonged circulation, enhanced permeation. Our manuscript tried to seek the attention of the researcher by framing some solutions of some existing troubleshoots of this bioactive component for enhanced applications and making the formulations feasible at an industrial production scale. This manuscript focuses on recent inventions as well, which can further be implemented at the community level. |
format | Online Article Text |
id | pubmed-8402133 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84021332021-08-29 Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets Chopra, Hitesh Dey, Protity Shuvra Das, Debashrita Bhattacharya, Tanima Shah, Muddaser Mubin, Sidra Maishu, Samka Peregrine Akter, Rokeya Rahman, Md. Habibur Karthika, Chenmala Murad, Waheed Qusty, Naeem Qusti, Safaa Alshammari, Eida M. Batiha, Gaber El-Saber Altalbawy, Farag M. A. Albooq, Mona I. M. Alamri, Badrieah M. Molecules Review Curcuma longa is very well-known medicinal plant not only in the Asian hemisphere but also known across the globe for its therapeutic and medicinal benefits. The active moiety of Curcuma longa is curcumin and has gained importance in various treatments of various disorders such as antibacterial, antiprotozoal, cancer, obesity, diabetics and wound healing applications. Several techniques had been exploited as reported by researchers for increasing the therapeutic potential and its pharmacological activity. Here, the dictum is the new room for the development of physicochemical, as well as biological, studies for the efficacy in target specificity. Here, we discussed nanoformulation techniques, which lend support to upgrade the characters to the curcumin such as enhancing bioavailability, increasing solubility, modifying metabolisms, and target specificity, prolonged circulation, enhanced permeation. Our manuscript tried to seek the attention of the researcher by framing some solutions of some existing troubleshoots of this bioactive component for enhanced applications and making the formulations feasible at an industrial production scale. This manuscript focuses on recent inventions as well, which can further be implemented at the community level. MDPI 2021-08-18 /pmc/articles/PMC8402133/ /pubmed/34443593 http://dx.doi.org/10.3390/molecules26164998 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chopra, Hitesh Dey, Protity Shuvra Das, Debashrita Bhattacharya, Tanima Shah, Muddaser Mubin, Sidra Maishu, Samka Peregrine Akter, Rokeya Rahman, Md. Habibur Karthika, Chenmala Murad, Waheed Qusty, Naeem Qusti, Safaa Alshammari, Eida M. Batiha, Gaber El-Saber Altalbawy, Farag M. A. Albooq, Mona I. M. Alamri, Badrieah M. Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets |
title | Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets |
title_full | Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets |
title_fullStr | Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets |
title_full_unstemmed | Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets |
title_short | Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets |
title_sort | curcumin nanoparticles as promising therapeutic agents for drug targets |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402133/ https://www.ncbi.nlm.nih.gov/pubmed/34443593 http://dx.doi.org/10.3390/molecules26164998 |
work_keys_str_mv | AT choprahitesh curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT deyprotityshuvra curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT dasdebashrita curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT bhattacharyatanima curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT shahmuddaser curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT mubinsidra curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT maishusamkaperegrine curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT akterrokeya curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT rahmanmdhabibur curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT karthikachenmala curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT muradwaheed curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT qustynaeem curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT qustisafaa curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT alshammarieidam curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT batihagaberelsaber curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT altalbawyfaragma curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT albooqmonaim curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets AT alamribadrieahm curcuminnanoparticlesaspromisingtherapeuticagentsfordrugtargets |