Cargando…

Establishment of an Intradermal Ear Injection Model of IL-17A and IL-36γ as a Tool to Investigate the Psoriatic Cytokine Network

Psoriasis is a chronic skin disease affecting 2–3% of the global population. The proinflammatory IL-17A is a key cytokine in psoriasis. Accumulating evidence has revealed that IL-36γ plays also a pathogenic role. To understand more precisely the role of the IL-17A–IL-36γ cytokine network in skin pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kluwig, David, Huth, Sebastian, Abdallah, Ali T., Pfaff, Carolina M., Fietkau, Katharina, Huth, Laura, Marquardt, Yvonne, Baron, Jens M., Lüscher, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402141/ https://www.ncbi.nlm.nih.gov/pubmed/34440590 http://dx.doi.org/10.3390/life11080846

Ejemplares similares

The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function
por: Pfaff, Carolina M., et al.
Publicado: (2017)

IL-36γ Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis
por: Bridgewood, Charlie, et al.
Publicado: (2018)

Altered serum levels of IL-36 cytokines (IL-36α, IL-36β, IL-36γ, and IL-36Ra) and their potential roles in Guillain-Barré syndrome
por: Zhao, Zhikang, et al.
Publicado: (2020)

Exploring the Role of IL-36 Cytokines as a New Target in Psoriatic Disease
por: Iznardo, Helena, et al.
Publicado: (2021)

IL-36 cytokines in autoimmunity and inflammatory disease
por: Ding, Liping, et al.
Publicado: (2017)

Interleukin(IL)-36α and IL-36γ Induce Proinflammatory Mediators from Human Colonic Subepithelial Myofibroblasts
por: Kanda, Toshihiro, et al.
Publicado: (2015)

Role of IL-36γ/IL-36R Signaling in Corneal Innate Defense Against Candida albicans Keratitis
por: Dai, Chenyang, et al.
Publicado: (2021)

PD36 - Evaluation of intracellular cytokines IL-2, IFNγ, IL-4 and IL-5 in children with atopic dermatitis and correlations with other immunological and epidemiological parameters
por: Koulouri, Maria, et al.
Publicado: (2014)

Cytokine IL-36γ Improves CAR T Cell Functionality and Induces Endogenous Anti-Tumor Response
por: Li, Xinghuo, et al.
Publicado: (2020)

Establishment of an Intradermal Canine IL-31-Induced Pruritus Model to Evaluate Therapeutic Candidates in Atopic Dermatitis
por: Pearson, Jason, et al.
Publicado: (2023)

IL-36, IL-37, and IL-38 Cytokines in Skin and Joint Inflammation: A Comprehensive Review of Their Therapeutic Potential
por: Boutet, Marie-Astrid, et al.
Publicado: (2019)

IL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic
por: Dong, Hongna, et al.
Publicado: (2022)

Increased serum IL-36β and IL-36γ levels in patients with neuromyelitis optica spectrum disorders: association with disease activity
por: Yang, Chun-Sheng, et al.
Publicado: (2019)

Mast Cell Cytokines IL-1, IL-33, and IL-36 Mediate Skin Inflammation in Psoriasis: A Novel Therapeutic Approach with the Anti-Inflammatory Cytokines IL-37, IL-38, and IL-1Ra
por: Conti, Pio, et al.
Publicado: (2021)

The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis
por: Madonna, Stefania, et al.
Publicado: (2019)

IL‐36γ and IL‐36Ra Reciprocally Regulate NSCLC Progression by Modulating GSH Homeostasis and Oxidative Stress‐Induced Cell Death
por: Wang, Peng, et al.
Publicado: (2021)

IL‐36γ and IL‐36Ra Reciprocally Regulate Colon Inflammation and Tumorigenesis by Modulating the Cell–Matrix Adhesion Network and Wnt Signaling
por: Yang, Wei, et al.
Publicado: (2022)

The Proinflammatory Cytokine IL-36γ Is a Global Discriminator of Harmless Microbes and Invasive Pathogens within Epithelial Tissues
por: Macleod, Thomas, et al.
Publicado: (2020)

Intradermal administration of IL-33 induces allergic airway inflammation
por: Han, Hongwei, et al.
Publicado: (2017)

Interleukin (IL)-1β Is a Strong Inducer of IL-36γ Expression in Human Colonic Myofibroblasts
por: Takahashi, Kenichiro, et al.
Publicado: (2015)

Structural insights into heme binding to IL-36α proinflammatory cytokine
por: Wißbrock, Amelie, et al.
Publicado: (2019)

Role of IL-36 Cytokines in the Regulation of Angiogenesis Potential of Trophoblast Cells
por: Murrieta-Coxca, José M., et al.
Publicado: (2020)

Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RN
por: Keermann, Maris, et al.
Publicado: (2015)

Cathepsin G cleaves and activates IL-36γ and promotes the inflammation of psoriasis
por: Guo, Jing, et al.
Publicado: (2019)

Expressions of IL4, IL10, and IFNγ cytokines genes during bacterial mastitis
por: Faaz, Rana A., et al.
Publicado: (2022)

The role of IL‐23 and the use of IL‐23 inhibitors in psoriatic arthritis
por: Fragoulis, George E., et al.
Publicado: (2022)

Identification of small‐molecule elastase inhibitors as antagonists of IL‐36 cytokine activation
por: Sullivan, Graeme P., et al.
Publicado: (2018)

IL-36 Cytokines: Regulators of Inflammatory Responses and Their Emerging Role in Immunology of Reproduction
por: Murrieta-Coxca, José Martin, et al.
Publicado: (2019)

IL-36 cytokines in inflammatory and malignant diseases: not the new kid on the block anymore
por: Byrne, James, et al.
Publicado: (2021)

IL-1α and IL-36 Family Cytokines Can Undergo Processing and Activation by Diverse Allergen-Associated Proteases
por: Frezza, Valentina, et al.
Publicado: (2022)

Serum IL-6 and IL-23 Levels and Their Correlation with Angiogenic Cytokines and Disease Activity in Ankylosing Spondylitis, Psoriatic Arthritis, and SAPHO Syndrome
por: Przepiera-Będzak, Hanna, et al.
Publicado: (2015)

Expression of Concern: Interleukin (IL)-1β Is a Strong Inducer of IL-36γ Expression in Human Colonic Myofibroblasts
Publicado: (2023)

MMP-3 plays a major role in calcium pantothenate-promoted wound healing after fractional ablative laser treatment
por: Huth, Sebastian, et al.
Publicado: (2021)

A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin
por: Johnson-Huang, Leanne M., et al.
Publicado: (2012)

IL-36γ is a pivotal inflammatory player in periodontitis-associated bone loss
por: Cloitre, Alexandra, et al.
Publicado: (2019)

Multifaceted Analysis of IL-23A- and/or EBI3-Including Cytokines Produced by Psoriatic Keratinocytes
por: Tachibana, Kota, et al.
Publicado: (2021)

The IL-17/IL-23 Axis and Its Genetic Contribution to Psoriatic Arthritis
por: Vecellio, Matteo, et al.
Publicado: (2021)

Dual inhibition of IL-17A and IL-17F in psoriatic disease
por: Iznardo, Helena, et al.
Publicado: (2021)

Functional role of IL-22 in psoriatic arthritis
por: Mitra, Anupam, et al.
Publicado: (2012)

IL-36α Exerts Proinflammatory Effects in Aspergillus fumigatus Keratitis of Mice Through the Pathway of IL-36α/IL-36R/NF-κB
por: Niu, Yawen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ii1kcfdg7ivp4ge9qr6tgu2qtq