An Indole-Based Fluorescent Chemosensor for Detecting Zn(2+) in Aqueous Media and Zebrafish

An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn(2+). IH-Sal displayed a marked fluorescence increment with Zn(2+). The detection limit (0.41 μM) of IH-Sal for Zn(2+) was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn(2+) in real wate...

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Detalles Bibliográficos
Autores principales: Choe, Donghwan, So, Haeri, Park, Soyoung, Lee, Hangyul, Chae, Ju Byeong, Kim, Jiwon, Kim, Ki-Tae, Kim, Cheal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402251/
https://www.ncbi.nlm.nih.gov/pubmed/34451041
http://dx.doi.org/10.3390/s21165591
Descripción
Sumario:An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn(2+). IH-Sal displayed a marked fluorescence increment with Zn(2+). The detection limit (0.41 μM) of IH-Sal for Zn(2+) was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn(2+) in real water samples. More significantly, IH-Sal could determine and depict the presence of Zn(2+) in zebrafish. The detecting mechanism of IH-Sal toward Zn(2+) was illustrated by fluorescence and UV–visible spectroscopy, DFT calculations, (1)H NMR titration and ESI mass.

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