An Indole-Based Fluorescent Chemosensor for Detecting Zn(2+) in Aqueous Media and Zebrafish

An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn(2+). IH-Sal displayed a marked fluorescence increment with Zn(2+). The detection limit (0.41 μM) of IH-Sal for Zn(2+) was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn(2+) in real wate...

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Autores principales: Choe, Donghwan, So, Haeri, Park, Soyoung, Lee, Hangyul, Chae, Ju Byeong, Kim, Jiwon, Kim, Ki-Tae, Kim, Cheal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402251/
https://www.ncbi.nlm.nih.gov/pubmed/34451041
http://dx.doi.org/10.3390/s21165591
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author Choe, Donghwan
So, Haeri
Park, Soyoung
Lee, Hangyul
Chae, Ju Byeong
Kim, Jiwon
Kim, Ki-Tae
Kim, Cheal
author_facet Choe, Donghwan
So, Haeri
Park, Soyoung
Lee, Hangyul
Chae, Ju Byeong
Kim, Jiwon
Kim, Ki-Tae
Kim, Cheal
author_sort Choe, Donghwan
collection PubMed
description An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn(2+). IH-Sal displayed a marked fluorescence increment with Zn(2+). The detection limit (0.41 μM) of IH-Sal for Zn(2+) was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn(2+) in real water samples. More significantly, IH-Sal could determine and depict the presence of Zn(2+) in zebrafish. The detecting mechanism of IH-Sal toward Zn(2+) was illustrated by fluorescence and UV–visible spectroscopy, DFT calculations, (1)H NMR titration and ESI mass.
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spelling pubmed-84022512021-08-29 An Indole-Based Fluorescent Chemosensor for Detecting Zn(2+) in Aqueous Media and Zebrafish Choe, Donghwan So, Haeri Park, Soyoung Lee, Hangyul Chae, Ju Byeong Kim, Jiwon Kim, Ki-Tae Kim, Cheal Sensors (Basel) Communication An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn(2+). IH-Sal displayed a marked fluorescence increment with Zn(2+). The detection limit (0.41 μM) of IH-Sal for Zn(2+) was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn(2+) in real water samples. More significantly, IH-Sal could determine and depict the presence of Zn(2+) in zebrafish. The detecting mechanism of IH-Sal toward Zn(2+) was illustrated by fluorescence and UV–visible spectroscopy, DFT calculations, (1)H NMR titration and ESI mass. MDPI 2021-08-19 /pmc/articles/PMC8402251/ /pubmed/34451041 http://dx.doi.org/10.3390/s21165591 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Choe, Donghwan
So, Haeri
Park, Soyoung
Lee, Hangyul
Chae, Ju Byeong
Kim, Jiwon
Kim, Ki-Tae
Kim, Cheal
An Indole-Based Fluorescent Chemosensor for Detecting Zn(2+) in Aqueous Media and Zebrafish
title An Indole-Based Fluorescent Chemosensor for Detecting Zn(2+) in Aqueous Media and Zebrafish
title_full An Indole-Based Fluorescent Chemosensor for Detecting Zn(2+) in Aqueous Media and Zebrafish
title_fullStr An Indole-Based Fluorescent Chemosensor for Detecting Zn(2+) in Aqueous Media and Zebrafish
title_full_unstemmed An Indole-Based Fluorescent Chemosensor for Detecting Zn(2+) in Aqueous Media and Zebrafish
title_short An Indole-Based Fluorescent Chemosensor for Detecting Zn(2+) in Aqueous Media and Zebrafish
title_sort indole-based fluorescent chemosensor for detecting zn(2+) in aqueous media and zebrafish
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402251/
https://www.ncbi.nlm.nih.gov/pubmed/34451041
http://dx.doi.org/10.3390/s21165591
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