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Efficacy and Safety of a Modified Vaccinia Ankara-NP+M1 Vaccine Combined with QIV in People Aged 65 and Older: A Randomised Controlled Clinical Trial (INVICTUS)
Background: Pre-existing T cell responses to influenza have been correlated with improved clinical outcomes in natural history and human challenge studies. We aimed to determine the efficacy, safety and immunogenicity of a T-cell directed vaccine in older people. Methods: This was a multicentre, par...
Autores principales: | Butler, Chris, Ellis, Chris, Folegatti, Pedro M., Swayze, Hannah, Allen, Julie, Bussey, Louise, Bellamy, Duncan, Lawrie, Alison, Eagling-Vose, Elizabeth, Yu, Ly-Mee, Shanyinde, Milensu, Mair, Catherine, Flaxman, Amy, Ewer, Katie, Gilbert, Sarah, Evans, Thomas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402379/ https://www.ncbi.nlm.nih.gov/pubmed/34451976 http://dx.doi.org/10.3390/vaccines9080851 |
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