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The Promise and Challenges of Cyclic Dinucleotides as Molecular Adjuvants for Vaccine Development
Cyclic dinucleotides (CDNs), originally discovered as bacterial second messengers, play critical roles in bacterial signal transduction, cellular processes, biofilm formation, and virulence. The finding that CDNs can trigger the innate immune response in eukaryotic cells through the stimulator of in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402453/ https://www.ncbi.nlm.nih.gov/pubmed/34452042 http://dx.doi.org/10.3390/vaccines9080917 |