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Ambient Light Rejection Integrated Circuit for Autonomous Adaptation on a Sub-Retinal Prosthetic System
This paper introduces an ambient light rejection (ALR) circuit for the autonomous adaptation of a subretinal implant system. The sub-retinal implants, located beneath a bipolar cell layer, are known to have a significant advantage in spatial resolution by integrating more than a thousand pixels, com...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402464/ https://www.ncbi.nlm.nih.gov/pubmed/34451078 http://dx.doi.org/10.3390/s21165638 |
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author | Kang, Hosung Choi, Hojong Kim, Jungsuk |
author_facet | Kang, Hosung Choi, Hojong Kim, Jungsuk |
author_sort | Kang, Hosung |
collection | PubMed |
description | This paper introduces an ambient light rejection (ALR) circuit for the autonomous adaptation of a subretinal implant system. The sub-retinal implants, located beneath a bipolar cell layer, are known to have a significant advantage in spatial resolution by integrating more than a thousand pixels, compared to epi-retinal implants. However, challenges remain regarding current dispersion in high-density retinal implants, and ambient light induces pixel saturation. Thus, the technical issues of ambient light associated with a conventional image processing technique, which lead to high power consumption and area occupation, are still unresolved. Thus, it is necessary to develop a novel image-processing unit to handle ambient light, considering constraints related to power and area. In this paper, we present an ALR circuit as an image-processing unit for sub-retinal implants. We first introduced an ALR algorithm to reduce the ambient light in conventional retinal implants; next, we implemented the ALR algorithm as an application-specific integrated chip (ASIC). The ALR circuit was fabricated using a standard 0.35-μm CMOS process along with an image-sensor-based stimulator, a sensor pixel, and digital blocks. As experimental results, the ALR circuit occupies an area of 190 µm(2), consumes a power of 3.2 mW and shows a maximum response time of 1.6 s at a light intensity of 20,000 lux. The proposed ALR circuit also has a pixel loss rate of 0.3%. The experimental results show that the ALR circuit leads to a sensor pixel (SP) being autonomously adjusted, depending on the light intensity. |
format | Online Article Text |
id | pubmed-8402464 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-84024642021-08-29 Ambient Light Rejection Integrated Circuit for Autonomous Adaptation on a Sub-Retinal Prosthetic System Kang, Hosung Choi, Hojong Kim, Jungsuk Sensors (Basel) Article This paper introduces an ambient light rejection (ALR) circuit for the autonomous adaptation of a subretinal implant system. The sub-retinal implants, located beneath a bipolar cell layer, are known to have a significant advantage in spatial resolution by integrating more than a thousand pixels, compared to epi-retinal implants. However, challenges remain regarding current dispersion in high-density retinal implants, and ambient light induces pixel saturation. Thus, the technical issues of ambient light associated with a conventional image processing technique, which lead to high power consumption and area occupation, are still unresolved. Thus, it is necessary to develop a novel image-processing unit to handle ambient light, considering constraints related to power and area. In this paper, we present an ALR circuit as an image-processing unit for sub-retinal implants. We first introduced an ALR algorithm to reduce the ambient light in conventional retinal implants; next, we implemented the ALR algorithm as an application-specific integrated chip (ASIC). The ALR circuit was fabricated using a standard 0.35-μm CMOS process along with an image-sensor-based stimulator, a sensor pixel, and digital blocks. As experimental results, the ALR circuit occupies an area of 190 µm(2), consumes a power of 3.2 mW and shows a maximum response time of 1.6 s at a light intensity of 20,000 lux. The proposed ALR circuit also has a pixel loss rate of 0.3%. The experimental results show that the ALR circuit leads to a sensor pixel (SP) being autonomously adjusted, depending on the light intensity. MDPI 2021-08-21 /pmc/articles/PMC8402464/ /pubmed/34451078 http://dx.doi.org/10.3390/s21165638 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kang, Hosung Choi, Hojong Kim, Jungsuk Ambient Light Rejection Integrated Circuit for Autonomous Adaptation on a Sub-Retinal Prosthetic System |
title | Ambient Light Rejection Integrated Circuit for Autonomous Adaptation on a Sub-Retinal Prosthetic System |
title_full | Ambient Light Rejection Integrated Circuit for Autonomous Adaptation on a Sub-Retinal Prosthetic System |
title_fullStr | Ambient Light Rejection Integrated Circuit for Autonomous Adaptation on a Sub-Retinal Prosthetic System |
title_full_unstemmed | Ambient Light Rejection Integrated Circuit for Autonomous Adaptation on a Sub-Retinal Prosthetic System |
title_short | Ambient Light Rejection Integrated Circuit for Autonomous Adaptation on a Sub-Retinal Prosthetic System |
title_sort | ambient light rejection integrated circuit for autonomous adaptation on a sub-retinal prosthetic system |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402464/ https://www.ncbi.nlm.nih.gov/pubmed/34451078 http://dx.doi.org/10.3390/s21165638 |
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