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Guiding the Immune Response to a Conserved Epitope in MSP2, an Intrinsically Disordered Malaria Vaccine Candidate

The malaria vaccine candidate merozoite surface protein 2 (MSP2) has shown promise in clinical trials and is in part responsible for a reduction in parasite densities. However, strain-specific reductions in parasitaemia suggested that polymorphic regions of MSP2 are immuno-dominant. One strategy to...

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Detalles Bibliográficos
Autores principales: Seow, Jeffrey, Das, Sreedam C., Morales, Rodrigo A. V., Ataide, Ricardo, Krishnarjuna, Bankala, Silk, Mitchell, Chalmers, David K., Richards, Jack, Anders, Robin F., MacRaild, Christopher A., Norton, Raymond S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402609/
https://www.ncbi.nlm.nih.gov/pubmed/34451980
http://dx.doi.org/10.3390/vaccines9080855

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