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Nedd8-Activating Enzyme Is a Druggable Host Dependency Factor of Human and Mouse Cytomegalovirus

Human cytomegalovirus causes diseases in individuals with insufficient immunity. Cytomegaloviruses exploit the ubiquitin proteasome pathway to manipulate the proteome of infected cells. The proteasome degrades ubiquitinated proteins. The family of cullin RING ubiquitin ligases (CRL) regulates the st...

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Detalles Bibliográficos
Autores principales:	Flores-Martínez, Yulia Alejandra, Le-Trilling, Vu Thuy Khanh, Trilling, Mirko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402636/ https://www.ncbi.nlm.nih.gov/pubmed/34452475 http://dx.doi.org/10.3390/v13081610

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