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The Endogenous RIG-I Ligand Is Generated in Influenza A-Virus Infected Cells

As a result of a viral infection, viral genomes are not only recognized by RIG-I, but also lead to the activation of RNase L, which cleaves cellular RNA to generate the endogenous RIG-I ligand (eRL). The eRL was previously identified as a specific sequence derived from the internal transcribed space...

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Detalles Bibliográficos
Autores principales: Steinberg, Julia, Wadenpohl, Timo, Jung, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402674/
https://www.ncbi.nlm.nih.gov/pubmed/34452429
http://dx.doi.org/10.3390/v13081564