Cargando…

Detection of IFNγ-Secreting CD4(+) and CD8(+) Memory T Cells in COVID-19 Convalescents after Stimulation of Peripheral Blood Mononuclear Cells with Live SARS-CoV-2

Background: New coronavirus SARS-CoV-2, a causative agent of the COVID-19 pandemic, has been circulating among humans since November 2019. Multiple studies have assessed the qualitative and quantitative characteristics of virus-specific immunity in COVID-19 convalescents, however, some aspects of th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matyushenko, Victoria, Isakova-Sivak, Irina, Kudryavtsev, Igor, Goshina, Arina, Chistyakova, Anna, Stepanova, Ekaterina, Prokopenko, Polina, Sychev, Ivan, Rudenko, Larisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402842/ https://www.ncbi.nlm.nih.gov/pubmed/34452355 http://dx.doi.org/10.3390/v13081490

Ejemplares similares

Truncation of NS1 Protein Enhances T Cell-Mediated Cross-Protection of a Live Attenuated Influenza Vaccine Virus Expressing Wild-Type Nucleoprotein
por: Prokopenko, Polina, et al.
Publicado: (2023)

In Vitro Stimulation with Live SARS-CoV-2 Suggests Th17 Dominance In Virus-Specific CD4+ T Cell Response after COVID-19
por: Kudryavtsev, Igor, et al.
Publicado: (2022)

Recombinant Live Attenuated Influenza Vaccine Viruses Carrying Conserved T Cell Epitopes of Human Adenoviruses Induce Functional Cytotoxic T Cell Responses and Protect Mice against both Infections
por: Isakova-Sivak, Irina, et al.
Publicado: (2020)

Prospects of and Barriers to the Development of Epitope-Based Vaccines against Human Metapneumovirus
por: Stepanova, Ekaterina, et al.
Publicado: (2020)

RDE Treatment Prevents Non-Specific Detection of SARS-CoV-2- and Influenza-Specific IgG Antibodies in Heat-Inactivated Serum Samples
por: Goshina, Arina, et al.
Publicado: (2023)

Conserved T-cell epitopes of respiratory syncytial virus (RSV) delivered by recombinant live attenuated influenza vaccine viruses efficiently induce RSV-specific lung-localized memory T cells and augment influenza-specific resident memory T-cell responses
por: Matyushenko, Victoria, et al.
Publicado: (2020)

Development of a T Cell-Based COVID-19 Vaccine Using a Live Attenuated Influenza Vaccine Viral Vector
por: Isakova-Sivak, Irina, et al.
Publicado: (2022)

Safety, Immunogenicity, and Protective Efficacy of a Chimeric A/B Live Attenuated Influenza Vaccine in a Mouse Model
por: Stepanova, Ekaterina, et al.
Publicado: (2021)

Ferristatin II Efficiently Inhibits SARS-CoV-2 Replication in Vero Cells
por: Sokolov, Alexey, et al.
Publicado: (2022)

Genotyping assay for differentiation of wild-type and vaccine viruses in subjects immunized with live attenuated influenza vaccine
por: Matyushenko, Victoria, et al.
Publicado: (2017)

Assessment of Immunogenic and Antigenic Properties of Recombinant Nucleocapsid Proteins of Five SARS-CoV-2 Variants in a Mouse Model
por: Rak, Alexandra, et al.
Publicado: (2023)

A promising inactivated whole-virion SARS-CoV-2 vaccine
por: Isakova-Sivak, Irina, et al.
Publicado: (2021)

Universal Live-Attenuated Influenza Vaccine Candidates Expressing Multiple M2e Epitopes Protect Ferrets against a High-Dose Heterologous Virus Challenge
por: Mezhenskaya, Daria, et al.
Publicado: (2021)

M2e-based universal influenza vaccines: a historical overview and new approaches to development
por: Mezhenskaya, Daria, et al.
Publicado: (2019)

Dysregulated Immune Responses in SARS-CoV-2-Infected Patients: A Comprehensive Overview
por: Kudryavtsev, Igor, et al.
Publicado: (2022)

Development and approval of live attenuated influenza vaccines based on Russian master donor viruses: Process challenges and success stories
por: Rudenko, Larisa, et al.
Publicado: (2016)

A Strategy to Elicit M2e-Specific Antibodies Using a Recombinant H7N9 Live Attenuated Influenza Vaccine Expressing Multiple M2e Tandem Repeats
por: Mezhenskaya, Daria, et al.
Publicado: (2021)

Sequential Immunization with Universal Live Attenuated Influenza Vaccine Candidates Protects Ferrets against a High-Dose Heterologous Virus Challenge
por: Isakova-Sivak, Irina, et al.
Publicado: (2019)

Contribution of Neuraminidase of Influenza Viruses to the Sensitivity to Sera Inhibitors and Reassortment Efficiency
por: Kiseleva, Irina, et al.
Publicado: (2014)

A Phase 1 Randomized Placebo-Controlled Study to Assess the Safety, Immunogenicity and Genetic Stability of a New Potential Pandemic H7N9 Live Attenuated Influenza Vaccine in Healthy Adults
por: Kiseleva, Irina, et al.
Publicado: (2020)

Cross-Reactivity of SARS-CoV-2 Nucleocapsid-Binding Antibodies and Its Implication for COVID-19 Serology Tests
por: Rak, Alexandra, et al.
Publicado: (2022)

Generation and Characterization of Universal Live-Attenuated Influenza Vaccine Candidates Containing Multiple M2e Epitopes
por: Kotomina, Tatiana, et al.
Publicado: (2020)

Chlamydia pneumoniae-Induced IFN-Gamma Responses in Peripheral Blood Mononuclear Cells Increase Numbers of CD4+ but Not CD8+ T Effector Memory Cells
por: Smith-Norowitz, Tamar A, et al.
Publicado: (2021)

Construction and Immunogenicity of a Novel Multivalent Vaccine Prototype Based on Conserved Influenza Virus Antigens
por: Kirsteina, Anna, et al.
Publicado: (2020)

Stochastic Modelling of HIV-1 Replication in a CD4 T Cell with an IFN Response
por: Sazonov, Igor, et al.
Publicado: (2023)

FoxP3(+)CD4(+), IFN-γ(+)CD4(+), and IFN-γ(+)CD8(+) cell levels in erosive and non-erosive types of oral lichen planus patients
por: Sun, Andy, et al.
Publicado: (2021)

CD100 on NK Cells Enhance IFNγ Secretion and Killing of Target Cells Expressing CD72
por: Mizrahi, Sa'ar, et al.
Publicado: (2007)

Cigarette Smoking Triggers Colitis by IFN-γ(+) CD4(+) T Cells
por: Lee, Gihyun, et al.
Publicado: (2017)

Two Live Attenuated Vaccines against Recent Low–and Highly Pathogenic H7N9 Influenza Viruses Are Safe and Immunogenic in Ferrets
por: Rudenko, Larisa, et al.
Publicado: (2018)

IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25(+)Foxp3(-) T cells
por: Tomala, Jakub, et al.
Publicado: (2021)

IFN-γ and CD38 in Hyperprogressive Cancer Development
por: Angelicola, Stefania, et al.
Publicado: (2021)

CD38 Ligation in Peripheral Blood Mononuclear Cells of Myeloma Patients Induces Release of Protumorigenic IL-6 and Impaired Secretion of IFNγ Cytokines and Proliferation
por: Fedele, Giorgio, et al.
Publicado: (2013)

Heterogenous CD8+ T Cell Maturation and ‘Polarization’ in Acute and Convalescent COVID-19 Patients
por: Kudryavtsev, Igor V., et al.
Publicado: (2022)

Evaluation of Mycobacterium tuberculosis specific antigen-stimulated CD27(−)CD38(+)IFN-γ(+)CD4(+) T cells for discrimination of active tuberculosis
por: Fang, Yong, et al.
Publicado: (2022)

Ectonucleotidase CD38 Demarcates Regulatory, Memory-Like CD8(+) T Cells with IFN-γ-Mediated Suppressor Activities
por: Bahri, Rajia, et al.
Publicado: (2012)

In Vitro Induction of Regulatory CD4(+)CD8α(+) T Cells by TGF-β, IL-7 and IFN-γ
por: Van Kaer, Luc, et al.
Publicado: (2013)

CD24 aggravates acute liver injury in autoimmune hepatitis by promoting IFN-γ production by CD4(+) T cells
por: Zheng, Chenhong, et al.
Publicado: (2018)

CD46 is a potent co-stimulatory receptor for expansion of human IFN-γ-producing CD8(+) T cells
por: Hansen, Aida S., et al.
Publicado: (2018)

Multifunctional, TNF-α and IFN-γ-Secreting CD4 and CD8 T Cells and CD8(High) T Cells Are Associated With the Cure of Human Visceral Leishmaniasis
por: Rodrigues, Lorranny Santana, et al.
Publicado: (2021)

Long-distance modulation of bystander tumor cells by CD8(+) T cell-secreted IFNγ
por: Hoekstra, Mirjam E., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0g0f2npbrnnufkjj9j0son61dl