Computational and Rational Design of Single-Chain Antibody against Tick-Borne Encephalitis Virus for Modifying Its Specificity

Tick-borne encephalitis virus (TBEV) causes 5−7 thousand cases of human meningitis and encephalitis annually. The neutralizing and protective antibody ch14D5 is a potential therapeutic agent. This antibody exhibits a high affinity for binding with the D3 domain of the glycoprotein E of the Far Easte...

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Detalles Bibliográficos
Autores principales: Baykov, Ivan K., Desyukevich, Pavel Y., Mikhaylova, Ekaterina E., Kurchenko, Olga M., Tikunova, Nina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402911/
https://www.ncbi.nlm.nih.gov/pubmed/34452359
http://dx.doi.org/10.3390/v13081494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8402911/
https://www.ncbi.nlm.nih.gov/pubmed/34452359
http://dx.doi.org/10.3390/v13081494

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