Mitral Annular Calcification in Marfan Syndrome: A 38-Year Follow-Up Observation

Background  Mitral annular calcification (MAC) associated with Marfan syndrome is rare in comparison with that frequently found in elderlies with valvular disease. Case Presentation  A 17-year-old woman with Marfan syndrome underwent mitral valve replacement for severe mitral regurgitation. Preopera...

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Autor principal: Horiuchi, Kazutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403017/
https://www.ncbi.nlm.nih.gov/pubmed/34466349
http://dx.doi.org/10.1055/s-0041-1728720
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author Horiuchi, Kazutaka
author_facet Horiuchi, Kazutaka
author_sort Horiuchi, Kazutaka
collection PubMed
description Background  Mitral annular calcification (MAC) associated with Marfan syndrome is rare in comparison with that frequently found in elderlies with valvular disease. Case Presentation  A 17-year-old woman with Marfan syndrome underwent mitral valve replacement for severe mitral regurgitation. Preoperative examination showed mitral valve prolapse and a dense C -shaped MAC. We evaluated MAC and adjacent area, respectively, in postoperative 18 and 38 years, and neither progression nor expansion of calcification was observed. Conclusion  MAC associated with Marfan syndrome is more likely to be caused by stresses due to valve prolapse than by connective tissue disorder.
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spelling pubmed-84030172021-08-30 Mitral Annular Calcification in Marfan Syndrome: A 38-Year Follow-Up Observation Horiuchi, Kazutaka Thorac Cardiovasc Surg Rep Background  Mitral annular calcification (MAC) associated with Marfan syndrome is rare in comparison with that frequently found in elderlies with valvular disease. Case Presentation  A 17-year-old woman with Marfan syndrome underwent mitral valve replacement for severe mitral regurgitation. Preoperative examination showed mitral valve prolapse and a dense C -shaped MAC. We evaluated MAC and adjacent area, respectively, in postoperative 18 and 38 years, and neither progression nor expansion of calcification was observed. Conclusion  MAC associated with Marfan syndrome is more likely to be caused by stresses due to valve prolapse than by connective tissue disorder. Georg Thieme Verlag KG 2021-01 2021-08-28 /pmc/articles/PMC8403017/ /pubmed/34466349 http://dx.doi.org/10.1055/s-0041-1728720 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Horiuchi, Kazutaka
Mitral Annular Calcification in Marfan Syndrome: A 38-Year Follow-Up Observation
title Mitral Annular Calcification in Marfan Syndrome: A 38-Year Follow-Up Observation
title_full Mitral Annular Calcification in Marfan Syndrome: A 38-Year Follow-Up Observation
title_fullStr Mitral Annular Calcification in Marfan Syndrome: A 38-Year Follow-Up Observation
title_full_unstemmed Mitral Annular Calcification in Marfan Syndrome: A 38-Year Follow-Up Observation
title_short Mitral Annular Calcification in Marfan Syndrome: A 38-Year Follow-Up Observation
title_sort mitral annular calcification in marfan syndrome: a 38-year follow-up observation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403017/
https://www.ncbi.nlm.nih.gov/pubmed/34466349
http://dx.doi.org/10.1055/s-0041-1728720
work_keys_str_mv AT horiuchikazutaka mitralannularcalcificationinmarfansyndromea38yearfollowupobservation

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