TLR4 Antagonism Reduces Movement-Induced Nociception and ATF-3 Expression in Experimental Osteoarthritis

INTRODUCTION: Toll-like receptor 4 (TLR4) is a pattern recognition receptor involved in the detection of pathogen-associated molecular patterns (PAMPs), but also a “danger-sensing” receptor that recognizes host-derived endogenous molecules called damage-associated molecular patterns (DAMPs). The inv...

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Detalles Bibliográficos
Autores principales: Ferreira-Gomes, Joana, Garcia, Miguel M, Nascimento, Diana, Almeida, Lígia, Quesada, Ernesto, Castro-Lopes, José Manuel, Pascual, David, Goicoechea, Carlos, Neto, Fani Lourença
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403032/
https://www.ncbi.nlm.nih.gov/pubmed/34466029
http://dx.doi.org/10.2147/JPR.S317877

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