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Efficacy and safety of hydroxychloroquine as pre-and post-exposure prophylaxis and treatment of COVID-19: A systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials.
BACKGROUND: Hydroxychloroquine (HCQ) is an anti-malarial and immunomodulatory drug considered a potential candidate for drug repurposing in COVID-19 due to their in vitro antiviral activity against SARS-CoV-2. Despite the potential antiviral effects and anti-inflammatory profile, the results based o...
Autores principales: | Martins-Filho, Paulo Ricardo, Ferreira, Lis Campos, Heimfarth, Luana, Araújo, Adriano Antunes de Souza, Quintans-Júnior, Lucindo José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403035/ https://www.ncbi.nlm.nih.gov/pubmed/34485970 http://dx.doi.org/10.1016/j.lana.2021.100062 |
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