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Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Higher Education Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403096/ https://www.ncbi.nlm.nih.gov/pubmed/33797032 http://dx.doi.org/10.1007/s13238-021-00824-z |
| _version_ | 1783745947470135296 |
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| author | Wei, Yu Zhou, Yingsi Liu, Yajing Ying, Wenqin Lv, Ruiming Zhao, Qimeng Zhou, Haibo Zuo, Erwei Sun, Yidi Yang, Hui Zhou, Changyang |
| author_facet | Wei, Yu Zhou, Yingsi Liu, Yajing Ying, Wenqin Lv, Ruiming Zhao, Qimeng Zhou, Haibo Zuo, Erwei Sun, Yidi Yang, Hui Zhou, Changyang |
| author_sort | Wei, Yu |
| collection | PubMed |
| description | |
| format | Online Article Text |
| id | pubmed-8403096 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Higher Education Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-84030962021-09-15 Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos Wei, Yu Zhou, Yingsi Liu, Yajing Ying, Wenqin Lv, Ruiming Zhao, Qimeng Zhou, Haibo Zuo, Erwei Sun, Yidi Yang, Hui Zhou, Changyang Protein Cell Letter Higher Education Press 2021-04-01 2021-09 /pmc/articles/PMC8403096/ /pubmed/33797032 http://dx.doi.org/10.1007/s13238-021-00824-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
| spellingShingle | Letter Wei, Yu Zhou, Yingsi Liu, Yajing Ying, Wenqin Lv, Ruiming Zhao, Qimeng Zhou, Haibo Zuo, Erwei Sun, Yidi Yang, Hui Zhou, Changyang Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos |
| title | Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos |
| title_full | Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos |
| title_fullStr | Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos |
| title_full_unstemmed | Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos |
| title_short | Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos |
| title_sort | indiscriminate ssdna cleavage activity of crispr-cas12a induces no detectable off-target effects in mouse embryos |
| topic | Letter |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403096/ https://www.ncbi.nlm.nih.gov/pubmed/33797032 http://dx.doi.org/10.1007/s13238-021-00824-z |
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