Challenges in LC–MS-based metabolomics for Alzheimer’s disease early detection: targeted approaches versus untargeted approaches

BACKGROUND: Alzheimer's disease (AD) is one of the most common causes of dementia in old people. Neuronal deficits such as loss of memory, language and problem-solving are severely compromised in affected patients. The molecular features of AD are Aβ deposits in plaques or in oligomeric structu...

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Detalles Bibliográficos
Autores principales: Reveglia, Pierluigi, Paolillo, Carmela, Ferretti, Gabriella, De Carlo, Armando, Angiolillo, Antonella, Nasso, Rosarita, Caputo, Mafalda, Matrone, Carmela, Di Costanzo, Alfonso, Corso, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403122/
https://www.ncbi.nlm.nih.gov/pubmed/34453619
http://dx.doi.org/10.1007/s11306-021-01828-w

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