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Current state of and need for enzyme engineering of 2-deoxy-D-ribose 5-phosphate aldolases and its impact

ABSTRACT: Deoxyribose-5-phosphate aldolases (DERAs, EC 4.1.2.4) are acetaldehyde-dependent, Class I aldolases catalyzing in nature a reversible aldol reaction between an acetaldehyde donor (C2 compound) and glyceraldehyde-3-phosphate acceptor (C3 compound, C3P) to generate deoxyribose-5-phosphate (C...

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Detalles Bibliográficos
Autores principales: Rouvinen, Juha, Andberg, Martina, Pääkkönen, Johan, Hakulinen, Nina, Koivula, Anu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403123/
https://www.ncbi.nlm.nih.gov/pubmed/34410440
http://dx.doi.org/10.1007/s00253-021-11462-0