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Nicotine Induces Maternal and Fetal Inflammatory Responses Which Predispose Intrauterine Infection Risk in a Rat Model

INTRODUCTION: Both smoking and infection adversely impact pregnancy. Previously, our group identified in a rodent model that 6 mg/kg/d nicotine increased the risk of fetal infection at gestation day (GD) 18. Here, we investigate lower nicotine doses. METHODS: Pregnant Sprague-Dawley rats received ni...

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Detalles Bibliográficos
Autores principales: von Chamier, Maria, Reyes, Leticia, Hayward, Linda F, Brown, Mary B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403242/
https://www.ncbi.nlm.nih.gov/pubmed/33894055
http://dx.doi.org/10.1093/ntr/ntab080