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Effects of Sodium‐Glucose Linked Transporter 2 Inhibition With Ertugliflozin on Mitochondrial Function, Energetics, and Metabolic Gene Expression in the Presence and Absence of Diabetes Mellitus in Mice

BACKGROUND: Inhibitors of the sodium‐glucose linked transporter 2 improve cardiovascular outcomes in patients with or without type 2 diabetes mellitus, but the effects on cardiac energetics and mitochondrial function are unknown. We assessed the effects of sodium‐glucose linked transporter 2 inhibit...

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Detalles Bibliográficos
Autores principales: Croteau, Dominique, Luptak, Ivan, Chambers, Jordan M., Hobai, Ion, Panagia, Marcello, Pimentel, David R., Siwik, Deborah A., Qin, Fuzhong, Colucci, Wilson S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403324/
https://www.ncbi.nlm.nih.gov/pubmed/34169737
http://dx.doi.org/10.1161/JAHA.120.019995

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