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Evaluation of low-pass genome sequencing in polygenic risk score calculation for Parkinson’s disease

BACKGROUND: Low-pass sequencing (LPS) has been extensively investigated for applicability to various genetic studies due to its advantages over genotype array data including cost-effectiveness. Predicting the risk of complex diseases such as Parkinson’s disease (PD) using polygenic risk score (PRS)...

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Detalles Bibliográficos
Autores principales:	Kim, Sungjae, Shin, Jong-Yeon, Kwon, Nak-Jung, Kim, Chang-Uk, Kim, Changhoon, Lee, Chong Sik, Seo, Jeong-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403377/ https://www.ncbi.nlm.nih.gov/pubmed/34454617 http://dx.doi.org/10.1186/s40246-021-00357-w

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