Cargando…

HDAC6 inactivates Runx2 promoter to block osteogenesis of bone marrow stromal cells in age-related bone loss of mice

BACKGROUND: Senile osteoporosis can cause bone fragility and increased risk for fractures and has been one of the most prevalent and severe diseases affecting the elderly population worldwidely. The underlying mechanisms are currently intensive areas of investigation. In age-related bone loss, decre...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Chao, Gao, Juan, Liang, Jun, Dai, Weixiang, Wang, Zhenfei, Xia, Mengjiao, Chen, Tao, Huang, Sen, Na, Jian, Xu, Long, Feng, Shiming, Dai, Kerong, Liu, Guangwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403388/
https://www.ncbi.nlm.nih.gov/pubmed/34454588
http://dx.doi.org/10.1186/s13287-021-02545-w