Cargando…

HDAC6 inactivates Runx2 promoter to block osteogenesis of bone marrow stromal cells in age-related bone loss of mice

BACKGROUND: Senile osteoporosis can cause bone fragility and increased risk for fractures and has been one of the most prevalent and severe diseases affecting the elderly population worldwidely. The underlying mechanisms are currently intensive areas of investigation. In age-related bone loss, decre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Chao, Gao, Juan, Liang, Jun, Dai, Weixiang, Wang, Zhenfei, Xia, Mengjiao, Chen, Tao, Huang, Sen, Na, Jian, Xu, Long, Feng, Shiming, Dai, Kerong, Liu, Guangwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403388/ https://www.ncbi.nlm.nih.gov/pubmed/34454588 http://dx.doi.org/10.1186/s13287-021-02545-w

Ejemplares similares

MicroRNAs Regulate Osteogenesis and Chondrogenesis of Mouse Bone Marrow Stromal Cells
por: Suomi, Salla, et al.
Publicado: (2008)

CCL3 in the bone marrow microenvironment causes bone loss and bone marrow adiposity in aged mice
por: Yu, Degang, et al.
Publicado: (2023)

Estradiol-enhanced osteogenesis of rat bone marrow stromal cells is associated with the JNK pathway
por: Song, Nan, et al.
Publicado: (2017)

Modifying oxygen tension affects bone marrow stromal cell osteogenesis for regenerative medicine
por: Inagaki, Yusuke, et al.
Publicado: (2017)

Roles of MicroRNAs in Osteogenesis or Adipogenesis Differentiation of Bone Marrow Stromal Progenitor Cells
por: Zhang, Ya-Li, et al.
Publicado: (2021)

A retrospective study of the mid-term efficacy of full-endoscopic annulus fibrosus suture following lumbar discectomy
por: Wang, Zhenfei, et al.
Publicado: (2022)

Overexpression of Bone Morphogenetic Protein-1 Promotes Osteogenesis of Bone Marrow Mesenchymal Stem Cells In Vitro
por: Su, Zhongping, et al.
Publicado: (2020)

Human Bone Marrow Stromal Cells: A Reliable, Challenging Tool for In Vitro Osteogenesis and Bone Tissue Engineering Approaches
por: Hempel, Ute, et al.
Publicado: (2016)

The interferon-inducible protein p202 promotes osteogenesis in mouse bone marrow stromal cells
por: Zhang, Linlin, et al.
Publicado: (2018)

Effect of Concentrated Growth Factor (CGF) on the Promotion of Osteogenesis in Bone Marrow Stromal Cells (BMSC) in vivo
por: Chen, Xia, et al.
Publicado: (2018)

Mechanical stimulation orchestrates the osteogenic differentiation of human bone marrow stromal cells by regulating HDAC1
por: Wang, J, et al.
Publicado: (2016)

Osteogenesis of bone marrow mesenchymal stem cell in hyperglycemia
por: Luo, Meng, et al.
Publicado: (2023)

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity
por: Hesse, Eric, et al.
Publicado: (2010)

Potency Biomarker Signature Genes from Multiparametric Osteogenesis Assays: Will cGMP Human Bone Marrow Mesenchymal Stromal Cells Make Bone?
por: Murgia, Alba, et al.
Publicado: (2016)

Cysteine Dioxygenase Type 1 Inhibits Osteogenesis by Regulating Wnt Signaling in Primary Mouse Bone Marrow Stromal Cells
por: Zhao, Xuefeng, et al.
Publicado: (2016)

Human bone marrow stem/stromal cell osteogenesis is regulated via mechanically activated osteocyte‐derived extracellular vesicles
por: Eichholz, Kian F., et al.
Publicado: (2020)

HDAC8, A Potential Therapeutic Target, Regulates Proliferation and Differentiation of Bone Marrow Stromal Cells in Fibrous Dysplasia
por: Xiao, Tao, et al.
Publicado: (2018)

Chrysosplenetin promotes osteoblastogenesis of bone marrow stromal cells via Wnt/β-catenin pathway and enhances osteogenesis in estrogen deficiency-induced bone loss
por: Hong, Guoju, et al.
Publicado: (2019)

Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways
por: Tang, Chen-Yi, et al.
Publicado: (2021)

Activating PIK3CA mutation promotes osteogenesis of bone marrow mesenchymal stem cells in macrodactyly
por: Cui, Hengqing, et al.
Publicado: (2020)

Dissecting the Role of Bone Marrow Stromal Cells on Bone Metastases
por: Buenrostro, Denise, et al.
Publicado: (2014)

Bone Marrow and Adipose Tissue Adenosine Receptors Effect on Osteogenesis and Adipogenesis
por: Eisenstein, Anna, et al.
Publicado: (2020)

Comparison of gingiva‐derived and bone marrow mesenchymal stem cells for osteogenesis
por: Sun, Quan, et al.
Publicado: (2019)

IL-6 Contributes to the Defective Osteogenesis of Bone Marrow Stromal Cells from the Vertebral Body of the Glucocorticoid-Induced Osteoporotic Mouse
por: Li, Xiang, et al.
Publicado: (2016)

Inhibition of Y1 Receptor Promotes Osteogenesis in Bone Marrow Stromal Cells via cAMP/PKA/CREB Pathway
por: Yu, Wei, et al.
Publicado: (2020)

Bone Regeneration Induced by Bone Porcine Block with Bone Marrow Stromal Stem Cells in a Minipig Model of Mandibular “Critical Size” Defect
por: Scarano, Antonio, et al.
Publicado: (2017)

Correction: Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways
por: Tang, Chen-Yi, et al.
Publicado: (2022)

ASPN Synergizes with HAPLN1 to Inhibit the Osteogenic Differentiation of Bone Marrow Mesenchymal Stromal Cells and Extracellular Matrix Mineralization of Osteoblasts
por: Zhou, Guohui, et al.
Publicado: (2023)

Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy
por: Yang, Mengyu, et al.
Publicado: (2017)

Dentin-Derived Inorganic Minerals Promote the Osteogenesis of Bone Marrow-Derived Mesenchymal Stem Cells: Potential Applications for Bone Regeneration
por: Lei, Gang, et al.
Publicado: (2020)

Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow
por: Song, Jie, et al.
Publicado: (2019)

Foxc2 regulates osteogenesis and angiogenesis of bone marrow mesenchymal stem cells
por: You, Wulin, et al.
Publicado: (2013)

Oncostatin M Maintains the Hematopoietic Microenvironment in the Bone Marrow by Modulating Adipogenesis and Osteogenesis
por: Sato, Fumi, et al.
Publicado: (2014)

A bone marrow niche-derived molecular switch between osteogenesis and hematopoiesis
por: Galán-Díez, Marta, et al.
Publicado: (2018)

Kartogenin Improves Osteogenesis of Bone Marrow Mesenchymal Stem Cells via Autophagy
por: Yan, Huichun, et al.
Publicado: (2022)

Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis
por: Matsushita, Yuki, et al.
Publicado: (2023)

Osteocalcin and Runx2 Expression in Anterior Maxillary Reconstructions Using Bone Xenografts Associated to Bone Marrow Aspirate Concentrate
por: Hergemöller, Daniel Fernando, et al.
Publicado: (2022)

Juglans regia L. extract promotes osteogenesis of human bone marrow mesenchymal stem cells through BMP2/Smad/Runx2 and Wnt/β-catenin pathways
por: Pang, Xianlun, et al.
Publicado: (2022)

Lentivirus transduced interleukin-1 receptor antagonist gene expression in murine bone marrow-derived mesenchymal stem cells in vitro
por: HE, TAO, et al.
Publicado: (2015)

Silencing of RBP-JK promotes the differentiation of bone marrow mesenchymal stem cells into vascular endothelial cells
por: Luo, Zhengliang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_crdb5mcdh0br79cnrm9aj2pnof