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High-fat diet-induced atherosclerosis promotes neurodegeneration in the triple transgenic (3 × Tg) mouse model of Alzheimer’s disease associated with chronic platelet activation

BACKGROUND: Epidemiological studies link vascular disease risk factors such as atherosclerosis, hypertension, and diabetes mellitus with Alzheimer’s disease (AD). Whether there are direct links between these conditions to β-amyloid (Aβ) aggregation and tau pathology is uncertain. METHODS: To investi...

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Detalles Bibliográficos
Autores principales:	Wang, Min, Lv, Junyan, Huang, Xiaoshan, Wisniewski, Thomas, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403418/ https://www.ncbi.nlm.nih.gov/pubmed/34454596 http://dx.doi.org/10.1186/s13195-021-00890-9

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