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Oct4-dependent FoxC1 activation improves the survival and neovascularization of mesenchymal stem cells under myocardial ischemia

BACKGROUND: The administration of mesenchymal stem cells (MSCs) remains the most promising approach for cardiac repair after myocardial infarct (MI). However, their poor survival and potential in the ischemic environment limit their therapeutic efficacy for heart repair after MI. The purpose of this...

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Detalles Bibliográficos
Autores principales: Ji, Zhou, Chen, Songsheng, Cui, Jin, Huang, Weiguang, Zhang, Rui, Wei, Jianrui, Zhang, Shaoheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403428/
https://www.ncbi.nlm.nih.gov/pubmed/34454602
http://dx.doi.org/10.1186/s13287-021-02553-w