Associations of immune cell homing gene signatures and infiltrates of lymphocyte subsets in human melanomas: discordance with CD163(+) myeloid cell infiltrates

BACKGROUND: Immune cells in the tumor microenvironment have prognostic value. In preclinical models, recruitment and infiltration of these cells depends on immune cell homing (ICH) genes such as chemokines, cell adhesion molecules, and integrins. We hypothesized ICH ligands CXCL9-11 and CCL2-5 would...

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Detalles Bibliográficos
Autores principales: Kwak, Minyoung, Erdag, Gulsun, Leick, Katie M., Bekiranov, Stefan, Engelhard, Victor H., Slingluff, Craig L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403429/
https://www.ncbi.nlm.nih.gov/pubmed/34454518
http://dx.doi.org/10.1186/s12967-021-03044-5

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