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Regulatory network analysis defines unique drug mechanisms of action and facilitates patient-drug matching in alopecia areata clinical trials

Not all therapeutics are created equal in regards to individual patients. The problem of identifying which compound will work best with which patient is a significant burden across all disease contexts. In the context of autoimmune diseases such as alopecia areata, several formulations of JAK/STAT i...

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Detalles Bibliográficos
Autores principales: Chen, James C., Dai, Zhenpeng, Christiano, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403543/
https://www.ncbi.nlm.nih.gov/pubmed/34504667
http://dx.doi.org/10.1016/j.csbj.2021.08.026