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Renal cell carcinoma with widespread metastasis in 19 years old young male – A rare case report

INTRODUCTION AND IMPORTANCE: Renal cell carcinoma is the most common malignant tumor of the kidney which occurs more frequently in men and older people than in women and young adults. Renal cell carcinoma is the second most common renal malignancy diagnosed among pediatric and adolescent patients co...

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Autores principales: Ghartimagar, Dilasma, Shrestha, Manish Kiran, Ghosh, Arnab, Ruwanpathirana, Ramitha Eshan, Regmi, Sudeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403580/
https://www.ncbi.nlm.nih.gov/pubmed/34455292
http://dx.doi.org/10.1016/j.ijscr.2021.106345
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author Ghartimagar, Dilasma
Shrestha, Manish Kiran
Ghosh, Arnab
Ruwanpathirana, Ramitha Eshan
Regmi, Sudeep
author_facet Ghartimagar, Dilasma
Shrestha, Manish Kiran
Ghosh, Arnab
Ruwanpathirana, Ramitha Eshan
Regmi, Sudeep
author_sort Ghartimagar, Dilasma
collection PubMed
description INTRODUCTION AND IMPORTANCE: Renal cell carcinoma is the most common malignant tumor of the kidney which occurs more frequently in men and older people than in women and young adults. Renal cell carcinoma is the second most common renal malignancy diagnosed among pediatric and adolescent patients comprising of 2% to 6% of renal cancers. CASE PRESENTATION: A 19 years old young adult male came with a history of epigastric and back pain, hematuria and weight loss. Per abdominal examination showed a palpable mass in the epigastric and left hypochondriac region. Radiological imaging showed diffuse infiltration of renal interstitium with multiple hypodense lesions in left kidney, renal vein infiltration, and lytic destruction of vertebral bodies and left superior pubic ramus. Fine needle aspiration cytology and trucut biopsy was taken which confirmed renal cell carcinoma, clear cell type with bone metastasis. CLINICAL DISCUSSION: Although most renal cell carcinoma is sporadic and relatively uncommon in young adults, the incidence of renal cell carcinoma in this age group has steadily increased. Young adults are less likely to receive diagnosis of renal cell carcinoma incidentally. A few reported pediatric series have shown that renal cell carcinoma is highly aggressive, tends to be invasive, and metastasizes to the lungs and bones. CONCLUSION: Young adult with clear cell renal cell carcinoma showing wide spread metastasis is rare. Since, young age is an independent prognostic factor for cancer-specific survival, early diagnosis of the tumor will be beneficial for patients.
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spelling pubmed-84035802021-09-02 Renal cell carcinoma with widespread metastasis in 19 years old young male – A rare case report Ghartimagar, Dilasma Shrestha, Manish Kiran Ghosh, Arnab Ruwanpathirana, Ramitha Eshan Regmi, Sudeep Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Renal cell carcinoma is the most common malignant tumor of the kidney which occurs more frequently in men and older people than in women and young adults. Renal cell carcinoma is the second most common renal malignancy diagnosed among pediatric and adolescent patients comprising of 2% to 6% of renal cancers. CASE PRESENTATION: A 19 years old young adult male came with a history of epigastric and back pain, hematuria and weight loss. Per abdominal examination showed a palpable mass in the epigastric and left hypochondriac region. Radiological imaging showed diffuse infiltration of renal interstitium with multiple hypodense lesions in left kidney, renal vein infiltration, and lytic destruction of vertebral bodies and left superior pubic ramus. Fine needle aspiration cytology and trucut biopsy was taken which confirmed renal cell carcinoma, clear cell type with bone metastasis. CLINICAL DISCUSSION: Although most renal cell carcinoma is sporadic and relatively uncommon in young adults, the incidence of renal cell carcinoma in this age group has steadily increased. Young adults are less likely to receive diagnosis of renal cell carcinoma incidentally. A few reported pediatric series have shown that renal cell carcinoma is highly aggressive, tends to be invasive, and metastasizes to the lungs and bones. CONCLUSION: Young adult with clear cell renal cell carcinoma showing wide spread metastasis is rare. Since, young age is an independent prognostic factor for cancer-specific survival, early diagnosis of the tumor will be beneficial for patients. Elsevier 2021-08-25 /pmc/articles/PMC8403580/ /pubmed/34455292 http://dx.doi.org/10.1016/j.ijscr.2021.106345 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ghartimagar, Dilasma
Shrestha, Manish Kiran
Ghosh, Arnab
Ruwanpathirana, Ramitha Eshan
Regmi, Sudeep
Renal cell carcinoma with widespread metastasis in 19 years old young male – A rare case report
title Renal cell carcinoma with widespread metastasis in 19 years old young male – A rare case report
title_full Renal cell carcinoma with widespread metastasis in 19 years old young male – A rare case report
title_fullStr Renal cell carcinoma with widespread metastasis in 19 years old young male – A rare case report
title_full_unstemmed Renal cell carcinoma with widespread metastasis in 19 years old young male – A rare case report
title_short Renal cell carcinoma with widespread metastasis in 19 years old young male – A rare case report
title_sort renal cell carcinoma with widespread metastasis in 19 years old young male – a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403580/
https://www.ncbi.nlm.nih.gov/pubmed/34455292
http://dx.doi.org/10.1016/j.ijscr.2021.106345
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